Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 10/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | THRB | P10828 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11919922 | 0.88 | THRB (0.60) | TP53TNKS2SMN1; SMN2LMNAHTT | |
| SCHEMBL11919934 | 0.78 | TP53 (0.72) | TP53TNKS2SMN1; SMN2LMNAHTT | |
| SCHEMBL11919919 | 0.73 | ALDH1A1 (0.73) | TP53TNKS2SMN1; SMN2LMNAHTT | |
| SCHEMBL13048271 | 0.72 | TP53 (0.84) | TP53TNKS2SMN1; SMN2LMNAHTT | |
| SCHEMBL11919923 | 0.71 | MAPT (0.76) | TP53TNKS2SMN1; SMN2LMNAHTT | |
| SCHEMBL13046998 | 0.69 | NPSR1 (0.90) | TP53TNKS2SMN1; SMN2LMNAHTT | |
| SCHEMBL13048272 | 0.67 | TSHR (0.83) | TP53TNKS2SMN1; SMN2LMNAHTT | |
| SCHEMBL1544348 | 0.66 | KCNH2 (0.46) | TP53SMN1; SMN2LMNAHTTMAPT | |
| SCHEMBL1544545 | 0.66 | LMNA (0.70) | TP53TNKS2SMN1; SMN2LMNAHTT | |
| SCHEMBL13048281 | 0.66 | TP53 (0.69) | TP53TNKS2SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139966-A1 | AZOLE DERIVATIVES AS WTN PATHWAY INHIBITORS | OSLO UNIVERSITY HOSPITAL HF (NO) | 2010-12-09 | — | — | WO | disclosed |