Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13621588 | 1.00 | LMNA (0.59) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14574458 | 0.85 | LMNA (0.56) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13426750 | 0.84 | LMNA (0.59) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14420891 | 0.84 | LMNA (0.59) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6859238 | 0.83 | LMNA (0.51) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6859243 | 0.83 | LMNA (0.51) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL17278268 | 0.82 | LMNA (0.54) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14516389 | 0.81 | ALDH1A1 (0.49) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14032267 | 0.80 | LMNA (0.51) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14370539 | 0.80 | LMNA (0.51) | LMNAHPGDHDAC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305030-A1 | NANOPARTICLES OF THERAPEUTIC AGENTS HAVING LOW WATER SOLUBILITY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305030-A1 | NANOPARTICLES OF THERAPEUTIC AGENTS HAVING LOW WATER SOLUBILITY | AQP1, CD44, AQP3 | LMNA 1111/4885HPGD 192/4885HDAC1 3501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.