Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 4/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.34 |
| ▸ | PTGES | O14684 | 3/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13048046 | 0.90 | MLYCD (0.38) | MLYCDPTGDR2TRPM8PIK3CGDYRK1A | |
| SCHEMBL13048114 | 0.89 | MLYCD (0.38) | MLYCDPTGDR2TRPM8PIK3CGDYRK1A | |
| SCHEMBL13048715 | 0.88 | DYRK1A (0.33) | PTGDR2TRPM8PIK3CGDYRK1A | |
| SCHEMBL17589949 | 0.82 | TRPM8 (0.32) | PTGDR2TRPM8PIK3CGDYRK1A | |
| SCHEMBL17589876 | 0.82 | PTGDR2 (0.34) | PTGDR2TRPM8PIK3CGDYRK1APIM1 | |
| SCHEMBL15109415 | 0.81 | MLYCD (0.43) | MLYCDPTGDR2PIK3CGDYRK1ACYP11B2 | |
| SCHEMBL13048607 | 0.81 | DYRK1A (0.35) | PTGDR2TRPM8PIK3CGDYRK1APIM1 | |
| SCHEMBL13048614 | 0.81 | PIK3CG (0.32) | PTGDR2TRPM8PIK3CGDYRK1APIM1 | |
| SCHEMBL18569325 | 0.79 | PTGES (0.32) | PTGDR2TRPM8PIK3CGDYRK1APTGES | |
| SCHEMBL13047988 | 0.79 | DYRK1A (0.33) | PTGDR2TRPM8PIK3CGDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614826-B1 | Process for preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2017-03-01 | — | — | EP | disclosed |
| EP-2427191-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-03-16 | — | — | EP | disclosed |
| US-9006446-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-04-14 | — | — | US | disclosed |
| US-9006446-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-04-14 | — | — | US | disclosed |
| US-20150045218-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2015-02-12 | — | — | US | disclosed |
| US-20150045218-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2015-02-12 | — | — | US | disclosed |
| US-8853246-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2014-10-07 | — | — | US | disclosed |
| US-8853246-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2014-10-07 | — | — | US | disclosed |
| US-20130089622-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130089622-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130072382-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-20130072382-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-8350044-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2013-01-08 | — | — | US | disclosed |
| US-8350044-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2013-01-08 | — | — | US | disclosed |
| US-20100292253-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2010-11-18 | — | — | US | disclosed |
| US-20100292253-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292253-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | MLYCD 401/4885PTGDR2 1142/4885TRPM8 2009/4885 |
| US-20130089622-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | MLYCD 401/4885PTGDR2 1142/4885TRPM8 2009/4885 |
| US-20150045218-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | MLYCD 401/4885PTGDR2 1142/4885TRPM8 2009/4885 |
| US-20130072382-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | MLYCD 401/4885PTGDR2 1142/4885TRPM8 2009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.