Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13713549 | 0.84 | POLB (0.41) | MAPTPOLBL3MBTL1TDP1CA2 | |
| SCHEMBL9963800 | 0.84 | APP (0.37) | RXRARXRBMAPTPOLBL3MBTL1 | |
| SCHEMBL682266 | 0.84 | ALDH1A1 (0.43) | RXRARXRBMAPTPOLBL3MBTL1 | |
| SCHEMBL2742186 | 0.81 | TDP1 (0.42) | MAPTPOLBL3MBTL1TDP1CA2 | |
| SCHEMBL15299024 | 0.78 | MAPT (0.35) | MAPTPOLBL3MBTL1TDP1CA2 | |
| SCHEMBL14491287 | 0.77 | CA1 (0.32) | CA2CA1CA12CA7CA9 | |
| SCHEMBL14607238 | 0.77 | ENPP2 (0.36) | CA2CA1CA12CA7CA9 | |
| SCHEMBL14278399 | 0.74 | CA1 (0.38) | MAPTL3MBTL1CA2CA1CA12 | |
| SCHEMBL21367618 | 0.74 | MAPT (0.49) | RXRARXRBMAPTPOLBL3MBTL1 | |
| SCHEMBL16591118 | 0.73 | NPC1 (0.46) | RXRARXRBL3MBTL1TDP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7833690-B2 | Photoacid generators and lithographic resists comprising the same | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2010-11-16 | — | — | US | disclosed |