SCHEMBL1305138

SCHEMBL1305138

C=Cc1ccc2ccccc2c1C1=CC(=O)NC1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.40
SIRT1 Q96EB6 1/20 0.40
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
PRKCB P05771 7/20 0.36
PRKCE Q02156 7/20 0.36
PRKD3 O94806 6/20 0.36
PRKCG P05129 6/20 0.36
PRKCA P17252 6/20 0.36
PRKCH P24723 6/20 0.36
PRKCI P41743 6/20 0.36
PRKCQ Q04759 6/20 0.36
PRKCZ Q05513 6/20 0.36
PRKCD Q05655 6/20 0.36
PRKD1 Q15139 6/20 0.36
DNMT1 P26358 1/20 0.34
CES1 P23141 1/20 0.34
TTR P02766 1/20 0.34
AKR1B1 P15121 1/20 0.34
NSD2 O96028 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5405972 0.79 DNMT1 (0.45) MEN1KMT2APRKCBPRKCEPRKD3
SCHEMBL31669073 0.78 CYP1A2 (0.42) KMT2APRKCBPRKCEPRKD3PRKCG
SCHEMBL11882241 0.78 PRKCB (0.40) MEN1KMT2APRKCBPRKCEPRKD3
SCHEMBL9228115 0.78 CYP1A2 (0.42) KMT2APRKCBPRKCEPRKD3PRKCG
SCHEMBL32670935 0.77 KDM4E (0.37) SIRT2SIRT1MEN1KMT2ADNMT1
SCHEMBL28074223 0.74 SIRT2 (0.37) SIRT2SIRT1MEN1KMT2APRKCB
SCHEMBL10704997 0.74 PDPK1 (0.36) SIRT2SIRT1MEN1KMT2ATTR
SCHEMBL3182292 0.72 ALDH1A1 (0.44) MEN1KMT2APRKCBPRKCEPRKD3
SCHEMBL8677827 0.72 GSK3B (0.38) SIRT2SIRT1ALDH1A1MAPTPKM
SCHEMBL27663126 0.72 PLAUR (0.41) PRKCBPRKCEPRKD3PRKCGPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2125976-B1 JETTABLE INKS WITH REDUCED FROTHING HEWLETT PACKARD DEVELOPMENT CO (US) 2018-12-05 EP disclosed
US-8052269-B2 Including a surfactant, and a color component dispersed in the jettable vehicle that exhibits a froth half life of less than 100 minutes; low printer noise, capability of high-speed recording, and multi-color recording HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2011-11-08 US disclosed
EP-2125976-A1 JETTABLE INKS WITH REDUCED PROTHING Hewlett-Packard Development Company, L.P. (US) 2009-12-02 EP disclosed
WO-2008094935-A1 JETTABLE INKS WITH REDUCED PROTHING HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2008-08-07 WO disclosed
US-20080178762-A1 Jettable inks with reduced frothing HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2008-07-31 US disclosed