SCHEMBL1305172

SCHEMBL1305172

CC(C)=CC(C=C(C)C)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.45
LMNA P02545 2/20 0.39
ADRA2A P08913 1/20 0.38
ADRA2C P18825 1/20 0.38
HIF1A Q16665 1/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
NOS2 P35228 1/20 0.38
CYP2D6 P10635 1/20 0.37
SRC P12931 1/20 0.37
ALDH1A1 P00352 1/20 0.37
DPP4 P27487 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3278200 0.87 CYP2D6 (0.41) TRPA1LMNAHPGDCYP2D6SRC
SCHEMBL6935686 0.80 TRPA1 (0.45) TRPA1LMNAADRA2AADRA2CHIF1A
SCHEMBL9222442 0.78 TRPA1 (0.64) TRPA1LMNAADRA2AADRA2CHIF1A
SCHEMBL4641824 0.78 TRPA1 (0.44) TRPA1LMNAADRA2AADRA2CHIF1A
SCHEMBL4945391 0.76 TRPA1 (0.42) TRPA1LMNAADRA2AADRA2CHIF1A
SCHEMBL563813 0.76 LMNA (0.45) TRPA1LMNAADRA2AADRA2CHIF1A
SCHEMBL12997088 0.76 TRPA1 (0.42) TRPA1LMNAADRA2AADRA2CHIF1A
SCHEMBL11127525 0.76 TRPA1 (0.42) TRPA1LMNAADRA2AADRA2CHIF1A
SCHEMBL11052765 0.76 TSHR (0.44) TRPA1LMNAADRA2AADRA2CHIF1A
SCHEMBL4313730 0.75 TRPA1 (0.41) TRPA1LMNAADRA2AADRA2CHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7012120-B2 Reworkable compositions of oxirane(s) or thirane(s)-containing resin and curing agent HENKEL CORPORATION (US) 2006-03-14 US claimed
US-20050288458-A1 Reworkable thermosetting resin composition KLEMARCZYK PHILIP T 2005-12-29 US claimed
CN-1232515-C Reworkable composition of ethylene oxide or thiirane containing resin and curing agent HENKEL CORP (US) 2005-12-21 CN claimed
EP-1268457-A4 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORP (US) 2005-07-20 EP claimed
JP-2003529643-A 2003-10-07 JP claimed
CN-1427831-A Reworkable composition of oxirane (S) or thiirane (S)-containing resin and curing agent HENKEL LOCTITE CORP (US) 2003-07-02 CN claimed
US-20030073770-A1 Reworkable compositions of oxirane(s) or thirane(s)-containing resin and curing agent Henkel IP & Holding GmbH (DE) 2003-04-17 US claimed
EP-1268457-A1 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORPORATION (US) 2003-01-02 EP claimed
WO-2001074798-A1 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORPORATION (US) 2001-10-11 WO claimed
US-8053587-B2 for mounting onto a circuit board semiconductor devices HENKEL CORPORATION (US) 2011-11-08 US disclosed
US-20080214840-A1 Reworkable thermosetting resin composition HENKEL CORPORATION (US) 2008-09-04 US disclosed
US-7012120-B2 Reworkable compositions of oxirane(s) or thirane(s)-containing resin and curing agent HENKEL CORPORATION (US) 2006-03-14 US disclosed
US-20050288458-A1 Reworkable thermosetting resin composition KLEMARCZYK PHILIP T 2005-12-29 US disclosed
CN-1232515-C Reworkable composition of ethylene oxide or thiirane containing resin and curing agent HENKEL CORP (US) 2005-12-21 CN disclosed
EP-1268457-A4 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORP (US) 2005-07-20 EP disclosed
CN-1431220-A Biosynthesis gene cluster of Nanchang UNIV SHANGHAI JIAOTONG (CN) 2003-07-23 CN disclosed
CN-1427831-A Reworkable composition of oxirane (S) or thiirane (S)-containing resin and curing agent HENKEL LOCTITE CORP (US) 2003-07-02 CN disclosed
US-20030073770-A1 Reworkable compositions of oxirane(s) or thirane(s)-containing resin and curing agent Henkel IP & Holding GmbH (DE) 2003-04-17 US disclosed
EP-1268457-A1 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORPORATION (US) 2003-01-02 EP disclosed
WO-2001074798-A1 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORPORATION (US) 2001-10-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080214840-A1 Reworkable thermosetting resin composition GSS, LSS, LRBA TRPA1 3525/4885LMNA 1478/4885ADRA2A 3112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.