SCHEMBL13052260

SCHEMBL13052260

[3H]CCNC(=S)NC1Cc2ccccc2C1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.51
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
MAPT P10636 2/20 0.41
GRM7 Q14831 3/20 0.40
LMNA P02545 3/20 0.40
HRH3 Q9Y5N1 1/20 0.40
MTNR1A P48039 3/20 0.39
MTNR1B P49286 3/20 0.39
POLB P06746 1/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
ALOX12 P18054 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL173810 0.89 IDO1 (0.56) IDO1MEN1KMT2AMAPTGRM7
SCHEMBL6153717 0.73 IDO1 (0.56) IDO1MAPTGRM7LMNAHRH3
SCHEMBL31141646 0.73 IDO1 (0.56) IDO1MAPTGRM7LMNAHRH3
SCHEMBL173391 0.70 IDO1 (0.61) IDO1MAPTGRM7LMNAHRH3
SCHEMBL173705 0.69 MTNR1A (0.53) IDO1MEN1KMT2AMAPTGRM7
SCHEMBL19977026 0.69 IDO1 (0.47) IDO1MEN1KMT2AMAPTGRM7
SCHEMBL3754299 0.69 MTNR1A (0.56) MEN1KMT2AMAPTLMNAMTNR1A
SCHEMBL3428492 0.69 IDO1 (0.59) IDO1MEN1KMT2AMAPTGRM7
SCHEMBL2794675 0.68 IDO1 (1.00) IDO1MEN1KMT2AMAPTGRM7
SCHEMBL28684223 0.67 MTNR1A (0.62) IDO1KMT2AMTNR1AMTNR1BPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100298138-A1 Aminoazoline and Urea Derivatives for Combating Animal Pests BASF SE (DE) 2010-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298138-A1 Aminoazoline and Urea Derivatives for Combating Animal Pests AADAT, INMT, SLC14A1 IDO1 38/4885MEN1 972/4885KMT2A 2055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.