Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13052513 | 0.86 | — | — | |
| SCHEMBL13388979 | 0.81 | RAB9A (0.57) | MEN1POLBMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL168807 | 0.81 | RAB9A (0.57) | MEN1POLBMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL13052521 | 0.78 | POLB (0.44) | MEN1POLBMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL13052505 | 0.78 | — | — | |
| SCHEMBL12302037 | 0.74 | KDM4E (0.47) | MEN1POLBMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL13052514 | 0.74 | POLB (0.32) | MEN1POLBMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL13052550 | 0.72 | — | — | |
| SCHEMBL12302000 | 0.71 | KDM4E (0.42) | MEN1POLBMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL14982709 | 0.70 | INSR (0.45) | MEN1POLBMAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7842811-B2 | Cyanine dye compounds | Life Technologies Corporation (US) | 2010-11-30 | — | — | US | disclosed |
| US-20100120051-A1 | CYANINE DYE COMPOUNDS | Life Technologies Corporation (US) | 2010-05-13 | — | — | US | disclosed |
| US-7655409-B2 | Have negatively charged substituent for fluorescent staining of DNA; used to distinguish DNA present in a sample from RNA | Life Technologies Corporation (US) | 2010-02-02 | — | — | US | disclosed |
| US-20090047683-A1 | CYANINE DYE COMPOUNDS | INVITROGEN CORPORATION (US) | 2009-02-19 | — | — | US | disclosed |
| US-7446202-B2 | Cyanine dye compounds | MOLECULAR PROBES, INC. (US) | 2008-11-04 | — | — | US | disclosed |