Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | HTT | P42858 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | BLM | P54132 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13388979 | 1.00 | RAB9A (0.57) | RAB9AHTTNPC1POLBMAPT | |
| SCHEMBL10023154 | 0.85 | RAB9A (0.47) | RAB9AHTTNPC1POLBMAPT | |
| SCHEMBL13098687 | 0.85 | RAB9A (0.47) | RAB9AHTTNPC1POLBMAPT | |
| SCHEMBL12302037 | 0.85 | KDM4E (0.47) | RAB9AHTTNPC1POLBMAPT | |
| SCHEMBL168809 | 0.84 | MEN1 (0.42) | RAB9AHTTNPC1POLBMAPT | |
| SCHEMBL16213660 | 0.84 | MEN1 (0.42) | RAB9AHTTNPC1POLBMAPT | |
| SCHEMBL13027035 | 0.84 | POLB (0.41) | RAB9AHTTNPC1POLBMAPT | |
| SCHEMBL5020857 | 0.83 | MAPT (0.41) | RAB9AHTTNPC1POLBMAPT | |
| SCHEMBL5020859 | 0.83 | MAPT (0.41) | RAB9AHTTNPC1POLBMAPT | |
| SCHEMBL10023161 | 0.83 | MAPT (0.41) | RAB9AHTTNPC1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10988810-B2 | Methods and materials for detection of mutations | PENTABASE APS (DK) | 2021-04-27 | — | — | US | disclosed |
| EP-3350347-B1 | METHODS AND MATERIALS FOR DETECTION OF MUTATIONS | PENTABASE APS (DK) | 2021-01-20 | — | — | EP | disclosed |
| US-20190085400-A1 | METHODS AND MATERIALS FOR DETECTION OF MUTATIONS | PENTABASE APS (DK) | 2019-03-21 | — | — | US | disclosed |
| WO-2017045689-A1 | METHODS AND MATERIALS FOR DETECTION OF MUTATIONS | PENTABASE APS (DK) | 2017-03-23 | — | — | WO | disclosed |
| US-20150247799-A1 | DETECTION OF IMMOBILIZED NUCLEIC ACID | LIFE TECHNOLOGIES CORP (US) | 2015-09-03 | — | — | US | disclosed |
| US-8969004-B2 | Detection of immobilized nucleic acid | Life Technologies Corporation (US) | 2015-03-03 | — | — | US | disclosed |
| US-20140076726-A1 | Detection of Immobilized Nucleic Acid | Life Technologies Corporation (US) | 2014-03-20 | — | — | US | disclosed |
| US-8378115-B2 | Monomethine dyes | Thermo Fisher Scientific (Milwaukee) LLC (US) | 2013-02-19 | — | — | US | disclosed |
| US-20130011927-A1 | DETECTION OF IMMOBILIZED NUCLEIC ACID | Life Technologies Corporation (US) | 2013-01-10 | — | — | US | disclosed |
| US-8173445-B1 | DNA intercalating agents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-05-08 | — | — | US | disclosed |
| US-7977057-B2 | Detection of immobilized nucleic acid | Life Technologies Corporation (US) | 2011-07-12 | — | — | US | disclosed |
| US-20100285470-A1 | MONOMETHINE DYES | Thermo Fisher Scientific (Milwaukee) LLC (US) | 2010-11-11 | — | — | US | disclosed |
| US-20100227331-A1 | DETECTION OF IMMOBILIZED NUCLEIC ACID | Life Technologies Corporation (US) | 2010-09-09 | — | — | US | disclosed |
| US-20100216665-A1 | DETECTION OF IMMOBILIZED NUCLEIC ACID | Life Technologies Corporation (US) | 2010-08-26 | — | — | US | disclosed |
| US-7727716-B2 | Detection of immobilized nucleic acid | Life Technologies Corporation (US) | 2010-06-01 | — | — | US | disclosed |
| US-20100068704-A1 | OLIGONUCLEOTIDES COMPRISING SIGNALLING PAIRS AND HYDROPHOBIC NUCLEOTIDES, STEMLESS BEACONS, FOR DETECTION OF NUCLEIC ACIDS, METHYLATION STATUS AND MUTANTS OF NUCLEIC ACIDS | PENTABASE APS (DK) | 2010-03-18 | — | — | US | disclosed |
| US-20100068704-A1 | OLIGONUCLEOTIDES COMPRISING SIGNALLING PAIRS AND HYDROPHOBIC NUCLEOTIDES, STEMLESS BEACONS, FOR DETECTION OF NUCLEIC ACIDS, METHYLATION STATUS AND MUTANTS OF NUCLEIC ACIDS | PENTABASE APS (DK) | 2010-03-18 | — | — | US | disclosed |
| US-7462468-B1 | DNA intercalating agents and methods of use | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2008-12-09 | — | — | US | disclosed |
| WO-2007104318-A2 | OLIGONUCLEOTIDES COMPRISING SIGNALLING PAIRS AND HYDROPHOBIC NUCLEOTIDES, STEMLESS BEACONS, FOR DETECTION OF NUCLEIC ACIDS, METHYLATION STATUS AND MUTANTS OF NUCLEIC ACIDS | PENTABASE APS (DK) | 2007-09-20 | — | — | WO | disclosed |
| WO-2007093816-A1 | DETECTION SYSTEM | ENIGMA DIAGNOSTICS LIMITED (GB) | 2007-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100068704-A1 | OLIGONUCLEOTIDES COMPRISING SIGNALLING PAIRS AND HYDROPHOBIC NUCLEOTIDES, STEMLESS BEACONS, FOR DETECTION OF NUCLEIC ACIDS, METHYLATION STATUS AND MUTANTS OF NUCLEIC ACIDS | DNMT1, DNMT3A, DNMT3L | RAB9A 3662/4885HTT 1316/4885NPC1 1858/4885 |
| US-20100227331-A1 | DETECTION OF IMMOBILIZED NUCLEIC ACID | DNMT3A, DDB1, DNMT1 | RAB9A 4462/4885HTT 1731/4885NPC1 3456/4885 |
| US-20100285470-A1 | MONOMETHINE DYES | POLRMT, METTL16, TRDMT1 | RAB9A 4016/4885HTT 872/4885NPC1 4685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.