Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12712836 | 1.00 | ELANE (0.34) | ELANECA1CA2CA9HCRTR2 | |
| SCHEMBL12712865 | 0.94 | ELANE (0.33) | ELANECA1CA2CA9HCRTR2 | |
| SCHEMBL12712584 | 0.89 | CA1 (0.33) | CA1CA2CA9MGAMGAA | |
| SCHEMBL12712870 | 0.88 | CA1 (0.32) | CA1CA2CA9MGAMGAA | |
| SCHEMBL12712723 | 0.88 | CA1 (0.31) | CA1CA2CA9HCRTR2HCRTR1 | |
| SCHEMBL13053728 | 0.86 | MMP1 (0.37) | ELANECA1CA2CA9L3MBTL1 | |
| SCHEMBL15989469 | 0.86 | CA1 (0.36) | ELANECA1CA2CA9HCRTR2 | |
| SCHEMBL13053787 | 0.86 | CA1 (0.36) | ELANECA1CA2CA9HCRTR2 | |
| SCHEMBL15989519 | 0.83 | HCRTR2 (0.36) | HCRTR2HCRTR1L3MBTL1 | |
| SCHEMBL12712843 | 0.82 | TBXAS1 (0.33) | ELANECA1CA2CA9HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170912-B3 | NEW PHOSPHORUS CONTAINING HETEROCYCLIC COMPOUNDS, SUGAR ANALOGUES, AND COMPOSITIONS HAVING ANTI-CANCER ACTIVITY CONTAINING THE SAME | CENTRE NAT RECH SCIENT (FR) | 2022-06-15 | — | — | EP | disclosed |
| US-20150376216-A1 | SUGAR-ANALOG PHOSPHORUS-CONTAINING HETEROCYCLES HAVING AN ANTI-METASTATIC ACTIVITY | UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES (FR) | 2015-12-31 | — | — | US | disclosed |
| US-20150376216-A1 | SUGAR-ANALOG PHOSPHORUS-CONTAINING HETEROCYCLES HAVING AN ANTI-METASTATIC ACTIVITY | UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES (FR) | 2015-12-31 | — | — | US | disclosed |
| WO-2014128429-A1 | SUGAR-ANALOG PHOSPHORUS-CONTAINING HETEROCYCLES HAVING AN ANTI-METASTATIC ACTIVITY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-08-28 | — | — | WO | disclosed |
| US-8383609-B2 | Phosphorus containing heterocyclic compounds, sugar analogues, and compositions having anti-cancer activity containing the same | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-02-26 | — | — | US | disclosed |
| US-8383609-B2 | Phosphorus containing heterocyclic compounds, sugar analogues, and compositions having anti-cancer activity containing the same | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-02-26 | — | — | US | disclosed |
| US-20100298272-A1 | PHOSPHORUS CONTAINING HETEROCYCLIC COMPOUNDS, SUGAR ANALOGUES, AND COMPOSITIONS HAVING ANTI-CANCER ACTIVITY CONTAINING THE SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-11-25 | — | — | US | disclosed |
| US-20100298272-A1 | PHOSPHORUS CONTAINING HETEROCYCLIC COMPOUNDS, SUGAR ANALOGUES, AND COMPOSITIONS HAVING ANTI-CANCER ACTIVITY CONTAINING THE SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-11-25 | — | — | US | disclosed |
| WO-2009004096-A1 | NEW PHOSPHORUS CONTAINING HETEROCYCLIC COMPOUNDS, SUGAR ANALOGUES, AND COMPOSITIONS HAVING ANTI-CANCER ACTIVITY CONTAINING THE SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298272-A1 | PHOSPHORUS CONTAINING HETEROCYCLIC COMPOUNDS, SUGAR ANALOGUES, AND COMPOSITIONS HAVING ANTI-CANCER ACTIVITY CONTAINING THE SAME | G6PC1, SLC5A1, HK1 | ELANE 4377/4885CA1 494/4885CA2 182/4885 |
| US-20150376216-A1 | SUGAR-ANALOG PHOSPHORUS-CONTAINING HETEROCYCLES HAVING AN ANTI-METASTATIC ACTIVITY | G6PC1, SLC5A1, FBP1 | ELANE 2004/4885CA1 466/4885CA2 277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.