SCHEMBL1305570

SCHEMBL1305570

CC(C=O)C1=CCCCC1(C)C

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.36
CCR2 P41597 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11135375 0.70
SCHEMBL14993156 0.68 TRPV1 (0.50) TRPV1CCR2
SCHEMBL27555704 0.68
SCHEMBL3937350 0.67 SMN1; SMN2 (0.31)
SCHEMBL14993445 0.64 TRPV1 (0.46) TRPV1
SCHEMBL28253228 0.63 CCR2 (0.33) CCR2
SCHEMBL1496194 0.62
SCHEMBL3330871 0.61 TRPV1 (0.44) TRPV1
SCHEMBL16499251 0.61 ALDH1A1 (0.33)
SCHEMBL23938696 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4055506-A SOAP, 2,6,6-TRIMETHYL-1-CYCLOHEXEN-1-YLACETALDEHYDE INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-10-25 US claimed
US-4036774-A Fragrant soap compositions containing alpha-substituted acetaldehyde and ketone INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-07-19 US claimed
US-4028279-A Novel fragrance compositions containing 2,6,6 trimethyl-1-cyclohexen-1-yl acetaldehyde and phenyl C6 ketone INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-06-07 US claimed
US-4026824-A COLOGNES INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-05-31 US claimed
US-4014351-A Novel tobacco flavoring and aroma compositions and tobaccos containing alpha-substituted acetaldehyde INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-03-29 US claimed
US-3959508-A Flavoring compositions containing mixture of 2,2,6-trimethyl-1-cyclohexen-1-ylacetaldehyde and 2,6,6-trimethyl-1-crotonyl-1,3-cyclohexadiene INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-05-25 US claimed
US-3956393-A PERALKANOIC ACID, HYDROLYSIS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-05-11 US claimed
US-3940499-A Food or flavor containing 2,6,6-trimethyl-1-cyclohexen-1-ylacetaldehyde INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-02-24 US claimed
CN-105439838-A Preparation method of 2-methyl-4-(2,6,6-trimethyl-1-cyclohexene-1-yl) -2-buten-1-aldehyde SHANGYU NHU BIOCHEMICAL IND CO LTD 2016-03-30 CN disclosed
US-8053592-B2 Method for producing optically active α-ionone TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-11-08 US disclosed
US-20110118500-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE a-IONONE TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-05-19 US disclosed
US-7902404-B2 Method for producing optically active α-ionone TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-03-08 US disclosed
US-20090216039-A1 Method for Producing Optically Active Alpha-Ionone TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-08-27 US disclosed
US-4026824-A COLOGNES INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-05-31 US disclosed
US-3940499-A Food or flavor containing 2,6,6-trimethyl-1-cyclohexen-1-ylacetaldehyde INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110118500-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE a-IONONE INF2, HSD17B1, AGL TRPV1 2104/4885CCR2 4876/4885
US-20090216039-A1 Method for Producing Optically Active Alpha-Ionone HSD17B1, ENO1, INF2 TRPV1 2099/4885CCR2 4873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.