Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | PNP | P00491 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.56 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21423035 | 1.00 | HIF1A (0.60) | HIF1APNPLMNATP53HTT | |
| SCHEMBL19666769 | 1.00 | HIF1A (0.60) | HIF1APNPLMNATP53HTT | |
| SCHEMBL14628598 | 1.00 | HIF1A (0.60) | HIF1APNPLMNATP53HTT | |
| SCHEMBL21263875 | 0.87 | TAS1R3 (0.48) | HIF1APNPLMNATP53HTT | |
| SCHEMBL24059955 | 0.84 | TAS1R3 (0.72) | — | |
| SCHEMBL20673218 | 0.84 | TAS1R3 (0.72) | — | |
| SCHEMBL20266264 | 0.84 | TAS1R3 (0.72) | — | |
| SCHEMBL20282807 | 0.84 | TAS1R3 (0.72) | — | |
| SCHEMBL20277518 | 0.84 | TAS1R3 (0.72) | — | |
| SCHEMBL14628596 | 0.81 | HIF1A (0.55) | HIF1APNPLMNATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210196723-A1 | Modulators of DUX4 for Regulation of Muscle Function | SONIC MASTER LTD (VG) | 2021-07-01 | — | — | US | disclosed |
| US-10933068-B2 | Modulators of DUX4 for regulation of muscle function | SONIC MASTER LIMITED (VG) | 2021-03-02 | — | — | US | disclosed |
| US-20190298727-A1 | MODULATORS OF DUX4 FOR REGULATION OF MUSCLE FUNCTION | SONIC MASTER LIMITED (VG) | 2019-10-03 | — | — | US | disclosed |
| US-7847075-B2 | 2-Azapurine compounds and their use | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2010-12-07 | — | — | US | disclosed |
| US-20090306360-A1 | 2-AZAPURINE COMPOUNDS AND THEIR USE | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210196723-A1 | Modulators of DUX4 for Regulation of Muscle Function | DDX21, MBNL1, MECP2 | HIF1A 2591/4885PNP 975/4885LMNA 1943/4885 |
| US-10933068-B2 | Modulators of DUX4 for regulation of muscle function | DDX21, MBNL1, MECP2 | HIF1A 2588/4885PNP 1004/4885LMNA 2031/4885 |
| US-20090306360-A1 | 2-AZAPURINE COMPOUNDS AND THEIR USE | ADAR, AMPD2, NSUN2 | HIF1A 3667/4885PNP 63/4885LMNA 4166/4885 |
| US-20190298727-A1 | MODULATORS OF DUX4 FOR REGULATION OF MUSCLE FUNCTION | DDX21, MBNL1, MECP2 | HIF1A 2588/4885PNP 1004/4885LMNA 2031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.