Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 9/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 9/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.34 |
| ▸ | LIPE | Q05469 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13002769 | 0.89 | GABRG2 (0.35) | HTR2AHTR2CHTR2BGABRG2GABRB3 | |
| SCHEMBL16480192 | 0.85 | GABRA1 (0.34) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL13357367 | 0.83 | GABRA1 (0.33) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL13002772 | 0.83 | HTR2A (0.37) | HTR2AHTR2CHTR2BGABRG2GABRB3 | |
| SCHEMBL13168023 | 0.80 | GABRA1 (0.33) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL10267137 | 0.80 | PDCD1 (0.35) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL13002829 | 0.80 | GABRG2 (0.39) | HTR2AHTR2CHTR2BGABRG2GABRB3 | |
| SCHEMBL13002855 | 0.78 | NPC1 (0.34) | LIPEMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL14411023 | 0.75 | GABRA1 (0.35) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL9883900 | 0.72 | KDM4E (0.36) | GABRG2GABRB3GABRA5GABRA3GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406216-B1 | HALOGENALKYLMETHYLENOXY-PHENYL-SUBSTITUTED KETOENOLS | BAYER IP GMBH (DE) | 2017-04-19 | — | — | EP | disclosed |
| EP-3153503-A1 | INTERMEDIATES FOR HALOGENOALKYLMETHYLENOXY-PHENYL-SUBSTITUTED KETOENOLS | Bayer Intellectual Property GmbH (DE) | 2017-04-12 | — | — | EP | disclosed |
| US-9045390-B2 | Haloalkylmethyleneoxyphenyl-substituted ketoenols | BAYER CROPSCIENCE AG (DE) | 2015-06-02 | — | — | US | disclosed |
| US-20140213813-A9 | Haloalkylmethyleneoxyphenyl-Substituted Ketoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-07-31 | — | — | US | disclosed |
| US-20140031577-A1 | Haloalkylmethyleneoxyphenyl-Substituted Ketoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-30 | — | — | US | disclosed |
| US-8518985-B2 | Haloalkylmethyleneoxyphenyl-substituted ketoenols | BAYER CROPSCIENCE AG (DE) | 2013-08-27 | — | — | US | disclosed |
| US-20100311593-A1 | Haloalkylmethyleneoxyphenyl-substituted ketoenols | BAYER CROPSCIENCE AG (DE) | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213813-A9 | Haloalkylmethyleneoxyphenyl-Substituted Ketoenols | PHYKPL, KCNE1, CSNK1E | HTR2A 4819/4885HTR2C 4302/4885HTR2B 4813/4885 |
| US-20140031577-A1 | Haloalkylmethyleneoxyphenyl-Substituted Ketoenols | PHYKPL, KCNE1, CSNK1E | HTR2A 4819/4885HTR2C 4302/4885HTR2B 4813/4885 |
| US-20100311593-A1 | Haloalkylmethyleneoxyphenyl-substituted ketoenols | PHYKPL, KCNE1, CSNK1E | HTR2A 4819/4885HTR2C 4302/4885HTR2B 4813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.