Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970553 | 0.94 | HCAR2 (0.58) | ATMTSHRHPGDHCAR2ALDH1A1 | |
| SCHEMBL8894081 | 0.92 | HCAR2 (0.59) | ATMTSHRHPGDHCAR2ALDH1A1 | |
| SCHEMBL8896661 | 0.92 | HCAR2 (0.59) | ATMTSHRHPGDHCAR2ALDH1A1 | |
| SCHEMBL1889620 | 0.92 | HCAR2 (0.59) | ATMTSHRHPGDHCAR2ALDH1A1 | |
| SCHEMBL8896935 | 0.92 | HCAR2 (0.59) | ATMTSHRHPGDHCAR2ALDH1A1 | |
| SCHEMBL8895422 | 0.92 | HCAR2 (0.59) | ATMTSHRHPGDHCAR2ALDH1A1 | |
| SCHEMBL8896113 | 0.92 | HCAR2 (0.59) | ATMTSHRHPGDHCAR2ALDH1A1 | |
| SCHEMBL6929525 | 0.92 | HCAR2 (0.59) | ATMTSHRHPGDHCAR2ALDH1A1 | |
| SCHEMBL128719 | 0.91 | ATM (0.65) | ATMTSHRHPGDHCAR2ALDH1A1 | |
| SCHEMBL131584 | 0.89 | ATM (0.63) | ATMTSHRHPGDHCAR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | PHARMACIA AND UPJOHN COMPANY LLC | 2005-09-08 | — | — | US | claimed |
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | claimed |
| CN-115192470-B | Oily composition | 宝丽化成工业有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-113693965-B | External preparation for skin for improving wrinkles | 宝丽化成工业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-115192470-A | Oily composition | 宝丽化成工业有限公司 | 2022-10-18 | — | — | CN | disclosed |
| EP-4008304-A2 | EXTERNAL PREPARATION FOR SKIN FOR WRINKLE IMPROVEMENT | Pola Chemical Industries Inc. (JP) | 2022-06-08 | — | — | EP | disclosed |
| EP-3476381-B1 | EXTERNAL PREPARATION FOR SKIN FOR WRINKLE IMPROVEMENT | POLA CHEM IND INC (JP) | 2021-12-22 | — | — | EP | disclosed |
| CN-113693965-A | External preparation for skin for improving wrinkles | 宝丽化成工业有限公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-109310585-B | External preparation for skin for improving wrinkles | 宝丽化成工业有限公司 | 2021-10-29 | — | — | CN | disclosed |
| US-20210030631-A1 | EXTERNAL PREPARATION FOR SKIN FOR WRINKLE IMPROVEMENT | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2021-02-04 | — | — | US | disclosed |
| US-20200368131-A1 | OIL-BASED COMPOSITION | POLA CHEM IND INC (JP) | 2020-11-26 | — | — | US | disclosed |
| EP-0254241-A1 | Pyrazolopyridine compounds, their preparation and use | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1988-01-27 | — | — | EP | disclosed |
| US-4614804-A | PRINTING, DYEING CELLULOSE | BASF AKTIENGESELLSCHAFT (DE) | 1986-09-30 | — | — | US | disclosed |
| EP-0074607-B1 | PROCESS FOR PREPARING TRIACETONE AMINE | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1986-01-15 | — | — | EP | disclosed |
| EP-0103278-A2 | Anthraquinone dyes and their use | BASF Aktiengesellschaft (DE) | 1984-03-21 | — | — | EP | disclosed |
| US-4386086-A | ENOL DERIVATIVES OF 2-ARYL-1,3-INDANDIONES | UNION CARBIDE CORPORATION (US) | 1983-05-31 | — | — | US | disclosed |
| EP-0008540-A2 | 2-aryl-1,3-indandione derivatives and compositions comprising them for controlling ectoparasitic acarina | UNION CARBIDE CORPORATION (US) | 1980-03-05 | — | — | EP | disclosed |
| US-4136100-A | BLUE-VIOLET TO GREEN-BLUE DYEINGS ON CELLULOSE TEXTILES | BASF AKTIENGESELLSCHAFT (DE) | 1979-01-23 | — | — | US | disclosed |
| US-4104043-A | Esters of 3-hydroxyindone compounds as herbicides and miticides | UNION CARBIDE CORPORATION (US) | 1978-08-01 | — | — | US | disclosed |
| US-4091006-A | MITICIDES AND HERBICIDES | UNION CARBIDE CORPORATION (US) | 1978-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210030631-A1 | EXTERNAL PREPARATION FOR SKIN FOR WRINKLE IMPROVEMENT | F12, CUTA, SQLE | ATM 2107/4885TSHR 3017/4885HPGD 1770/4885 |
| US-20200368131-A1 | OIL-BASED COMPOSITION | CUTA, EBP, LIPA | ATM 626/4885TSHR 4625/4885HPGD 450/4885 |
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | IL4, ARG2, CASP4 | ATM 1321/4885TSHR 1759/4885HPGD 1845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.