Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | MC4R | P32245 | 1/20 | 0.63 |
| ▸ | CHKA | P35790 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | NCF1 | P14598 | 1/20 | 0.57 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.53 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21650862 | 0.89 | NPC1 (0.63) | LMNAMC4RCHKANPC1TP53 | |
| SCHEMBL17465319 | 0.89 | CHKA (0.82) | CHKACA2NCF1PRMT6KDM4E | |
| SCHEMBL13228061 | 0.84 | HRH3 (0.68) | NCF1KDM4EALDH1A1MBTD1L3MBTL3 | |
| SCHEMBL306744 | 0.84 | LMNA (0.69) | LMNAMC4RCHKANPC1TP53 | |
| SCHEMBL25565610 | 0.84 | ALDH1A1 (0.66) | LMNANPC1TP53RAB9AHPGD | |
| SCHEMBL5912658 | 0.83 | LMNA (0.73) | LMNAMC4RCHKANPC1TP53 | |
| SCHEMBL15390746 | 0.83 | LMNA (0.62) | LMNAMC4RCHKANPC1TP53 | |
| SCHEMBL13062773 | 0.82 | HRH3 (0.72) | NCF1KDM4EALDH1A1MBTD1L3MBTL3 | |
| SCHEMBL18753409 | 0.82 | MC4R (0.61) | LMNAMC4RCHKANPC1TP53 | |
| Hydrochloric Acid SCHEMBL3868716 | 0.81 | LMNA (0.71) | LMNAMC4RCHKANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3241554-A1 | QUINOLINE-8-SULFONAMIDE DERIVATES HAVING AN ANTICANCER ACTIVITY | Agios Pharmaceuticals, Inc. (US) | 2017-11-08 | — | — | EP | disclosed |
| US-20100317644-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317644-A1 | Substituted Sulfonamide Compounds | SULT2A1, STS, SULT1A1 | LMNA 2964/4885MC4R 1834/4885CHKA 4252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.