Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3998104 | 0.91 | MEN1 (0.41) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL10263861 | 0.89 | MEN1 (0.39) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL14413091 | 0.86 | LMNA (0.40) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL10264452 | 0.84 | LMNA (0.39) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL25057512 | 0.81 | MEN1 (0.56) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL9717110 | 0.81 | MEN1 (0.56) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL10257305 | 0.81 | ACACB (0.37) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL23867079 | 0.79 | LMNA (0.62) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL8425014 | 0.79 | MEN1 (0.50) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL5382183 | 0.79 | ALDH1A1 (0.41) | MEN1CYP3A4ALOX15KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100316657-A1 | Synthetic Archaeal Glycolipid Adjuvants | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2010-12-16 | — | — | US | disclosed |