Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13063123 | 0.83 | ALDH1A1 (0.32) | ALDH1A1CYP3A4HPGDMEN1KMT2A | |
| SCHEMBL13063115 | 0.82 | ABCB1 (0.32) | ALDH1A1MEN1KMT2ACRHR1 | |
| SCHEMBL12046796 | 0.81 | HTT (0.44) | LMNAALDH1A1CYP3A4HPGDMEN1 | |
| SCHEMBL13063372 | 0.78 | KEAP1 (0.41) | LMNACYP3A4HPGDMEN1KMT2A | |
| SCHEMBL12012115 | 0.77 | BDKRB1 (0.40) | LMNAMEN1KMT2ATSHRBDKRB1 | |
| SCHEMBL13063117 | 0.76 | CYP3A4 (0.40) | LMNAALDH1A1CYP3A4HPGDMEN1 | |
| SCHEMBL13063122 | 0.76 | BDKRB1 (0.33) | LMNAALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL13063141 | 0.76 | KDM4E (0.37) | LMNAALDH1A1CYP3A4HPGDMEN1 | |
| SCHEMBL13063362 | 0.75 | TDP1 (0.38) | CYP3A4HPGDMEN1KMT2ATSHR | |
| SCHEMBL13063377 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858618-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-28 | — | — | US | disclosed |
| US-20090137545-A1 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137545-A1 | Compounds | ADORA2B, ABCB11, CYP11B1 | LMNA 3483/4885ALDH1A1 279/4885CYP3A4 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.