SCHEMBL13063368

SCHEMBL13063368

C=CC1(CC(=O)O)CC(C)=CC(C)(C)C1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13063367 0.83 KMT2A (0.36) L3MBTL1
SCHEMBL3079293 0.70 PTGS1 (0.31) PTGS1
SCHEMBL2693566 0.66
SCHEMBL6860579 0.63 CYP2C19 (0.45) PTGS1
SCHEMBL4929033 0.63 CYP2C19 (0.40) PTGS1
SCHEMBL19746426 0.62 GABRA5 (0.31)
SCHEMBL16150052 0.62 CYP2C19 (0.48) PTGS1
SCHEMBL4689732 0.62 CYP2C19 (0.48) PTGS1
SCHEMBL4689889 0.59 CYP2C19 (0.32)
SCHEMBL27946314 0.55 ALDH1A1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2260839-A2 Combination therapy using 1-aminocyclohexane derivatives and acetylcholinesterase inhibitors Merz Pharma GmbH & Co. KGaA (DE) 2010-12-15 EP disclosed