Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13063409 | 0.83 | PTGS2 (0.46) | TDP1TSHRALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL10479216 | 0.80 | TDP1 (0.54) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL13802372 | 0.78 | TDP1 (0.50) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL13063418 | 0.78 | TDP1 (0.45) | TDP1TSHRGAAMAOA | |
| SCHEMBL223169 | 0.77 | PTGS2 (0.57) | TDP1TSHRALDH1A1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7327250 | 0.76 | PTGS2 (0.55) | TDP1TSHRALDH1A1CYP3A4RAB9A | |
| SCHEMBL8167105 | 0.75 | ALDH1A1 (0.58) | TDP1TSHRALDH1A1CYP3A4RAB9A | |
| SCHEMBL12832801 | 0.74 | HDAC1 (0.50) | TDP1TSHRRAB9ANPC1 | |
| SCHEMBL3973631 | 0.73 | PTGS2 (0.53) | TDP1TSHRMAPK1ALDH1A1RAB9A | |
| SCHEMBL6684430 | 0.72 | TDP1 (0.54) | TDP1TSHRMAPK1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937182-B1 | BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES | BEZWADA BIOMEDICAL LLC (US) | 2010-12-15 | — | — | EP | disclosed |