SCHEMBL13063792

SCHEMBL13063792

CCC(C)(CC)Oc1ccc(C(C)(C)c2ccc(OC(=O)C(C)C)c(C)c2)cc1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.39
VDR P11473 2/20 0.38
ALOX15 P16050 1/20 0.38
ACACB O00763 1/20 0.37
MRGPRX4 Q96LA9 2/20 0.36
FBP1 P09467 1/20 0.35
PPARD Q03181 1/20 0.35
PPARA Q07869 1/20 0.35
ADRB2 P07550 1/20 0.35
ADRA2A P08913 1/20 0.35
DRD2 P14416 1/20 0.35
ADRA2C P18825 1/20 0.35
DRD1 P21728 1/20 0.35
ADRA1A P35348 1/20 0.35
DRD3 P35462 1/20 0.35
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
RXRG P48443 1/20 0.35
AR P10275 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13063790 0.94 CYP2C19 (0.41) CYP2C19ALOX15ACACBMRGPRX4FBP1
SCHEMBL13328519 0.92 VDR (0.42) VDRALOX15FBP1ADRB2ADRA2A
SCHEMBL13758548 0.83 VDR (0.41) VDRALOX15FBP1ADRB2ADRA2A
SCHEMBL13708508 0.82 VDR (0.40) VDRFBP1ARKMT2AHDAC3
SCHEMBL13063789 0.82 ALOX15 (0.42) VDRALOX15ACACBADRB2ADRA2A
SCHEMBL13063794 0.80 ALOX15 (0.46) CYP2C19ALOX15ACACBFBP1PPARD
SCHEMBL13061729 0.79 VDR (0.44) CYP2C19VDRARNPSR1KDM4E
SCHEMBL16298983 0.78 ALOX15 (0.41) VDRALOX15ADRB2ADRA2ADRD2
SCHEMBL13063796 0.78 ALOX15 (0.47) VDRALOX15FBP1ADRB2ADRA2A
SCHEMBL17130505 0.77 ALOX15 (0.41) VDRALOX15ADRB2ADRA2ADRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100329748-A1 DEVELOPING DEVICE AND IMAGE FORMING APPARATUS USING THE DEVELOPING DEVICE RICOH COMPANY, LTD. (JP) 2010-12-30 US disclosed