Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | CFD | P00746 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13328519 | 0.86 | VDR (0.42) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL14701717 | 0.85 | L3MBTL1 (0.37) | ALOX15L3MBTL1PPARGCFDVDR | |
| SCHEMBL13063794 | 0.84 | ALOX15 (0.46) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL14342686 | 0.80 | ESR1 (0.59) | ESR1ESR2 | |
| SCHEMBL13063792 | 0.78 | CYP2C19 (0.39) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL13758548 | 0.77 | VDR (0.41) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL13708508 | 0.76 | VDR (0.40) | VDRFBP1ESR1KMT2A | |
| SCHEMBL28371142 | 0.75 | ADRB2 (0.56) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL14679469 | 0.74 | L3MBTL1 (0.37) | L3MBTL1PPARGCFDVDROPRK1 | |
| SCHEMBL13063789 | 0.73 | ALOX15 (0.42) | ALOX15ADRB2ADRA2ADRD2ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100329748-A1 | DEVELOPING DEVICE AND IMAGE FORMING APPARATUS USING THE DEVELOPING DEVICE | RICOH COMPANY, LTD. (JP) | 2010-12-30 | — | — | US | disclosed |