Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13328519 | 0.87 | VDR (0.42) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL13063790 | 0.85 | CYP2C19 (0.41) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL13063792 | 0.82 | CYP2C19 (0.39) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL13758548 | 0.78 | VDR (0.41) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL13708508 | 0.77 | VDR (0.40) | KMT2ARORCESR1VDRATM | |
| SCHEMBL14679468 | 0.75 | ESR1 (0.34) | KMT2AMEN1L3MBTL1ESR1ESR2 | |
| SCHEMBL14173149 | 0.73 | KLF10 (0.39) | KMT2AL3MBTL1RORCESR1ESR2 | |
| SCHEMBL13061729 | 0.73 | VDR (0.44) | KMT2AMEN1HTTESR1VDR | |
| SCHEMBL16298983 | 0.73 | ALOX15 (0.41) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL13063796 | 0.73 | ALOX15 (0.47) | ALOX15ADRB2ADRA2ADRD2ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100329748-A1 | DEVELOPING DEVICE AND IMAGE FORMING APPARATUS USING THE DEVELOPING DEVICE | RICOH COMPANY, LTD. (JP) | 2010-12-30 | — | — | US | disclosed |