Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 15/20 | 0.47 |
| ▸ | CMA1 | P23946 | 2/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1223895 | 0.79 | CREBBP (0.57) | TRPM5MEN1KMT2ACREBBP | |
| SCHEMBL1223744 | 0.79 | TRPM5 (0.53) | TRPM5MEN1KMT2AMCL1 | |
| SCHEMBL11086800 | 0.65 | CMA1 (0.41) | CMA1CTSGMCL1 | |
| SCHEMBL27774971 | 0.64 | CNR1 (0.41) | TRPM5MEN1KMT2AMCL1 | |
| SCHEMBL2036321 | 0.64 | ALDH1A1 (0.54) | MEN1KMT2AMCL1 | |
| SCHEMBL6866591 | 0.64 | CREBBP (0.68) | CMA1CTSGMEN1KMT2AMCL1 | |
| SCHEMBL19048575 | 0.63 | MCL1 (0.43) | MEN1KMT2AMCL1 | |
| Fumaric Acid SCHEMBL8959767 | 0.63 | TRPM5 (0.47) | TRPM5 | |
| SCHEMBL28131230 | 0.62 | NR4A2 (0.44) | TRPM5KMT2A | |
| SCHEMBL26965716 | 0.62 | HTR2A (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132615-A1 | HYDRAZONE COMPOUNDS AND THEIR USE | STEIN PHILIP (US) | 2010-11-18 | — | — | WO | disclosed |