Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 15/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1224923 | 0.82 | MEN1 (0.62) | TRPM5MEN1KMT2AMAPTNPC1 | |
| SCHEMBL13064359 | 0.79 | TRPM5 (0.47) | TRPM5MEN1KMT2AMCL1 | |
| SCHEMBL1223895 | 0.78 | CREBBP (0.57) | TRPM5MEN1KMT2AKDM4E | |
| SCHEMBL1225094 | 0.76 | TRPM5 (0.55) | TRPM5MEN1KMT2AMAPTKDM4E | |
| SCHEMBL1224778 | 0.71 | TRPM5 (1.00) | TRPM5 | |
| SCHEMBL1225001 | 0.70 | TRPM5 (1.00) | TRPM5 | |
| SCHEMBL1223718 | 0.69 | TRPM5 (0.56) | TRPM5MEN1KMT2AMAPTNPC1 | |
| SCHEMBL12881193 | 0.68 | LMNA (0.69) | TRPM5KMT2AMAPTKDM4E | |
| SCHEMBL27774971 | 0.66 | CNR1 (0.41) | TRPM5MEN1KMT2AGAAMCL1 | |
| SCHEMBL4413713 | 0.66 | KMT2A (0.43) | MEN1KMT2AMAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110033393-A1 | Hydrazone Compounds and Their Use | REDPOINT BIO CORPORATION | 2011-02-10 | — | — | US | disclosed |
| WO-2010132615-A1 | HYDRAZONE COMPOUNDS AND THEIR USE | STEIN PHILIP (US) | 2010-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110033393-A1 | Hydrazone Compounds and Their Use | TRPM5, TRPV5, TRPM8 | TRPM5 1/4885MEN1 206/4885KMT2A 2304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.