Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA8 | P11142 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.36 |
| ▸ | CDK2 | P24941 | 3/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2786518 | 1.00 | HSPA8 (0.37) | HSPA8DYRK1ACCNA2CDK2CCNA1 | |
| SCHEMBL4012901 | 0.93 | SRC (0.38) | HSPA8DYRK1ACCNA2CDK2CCNA1 | |
| SCHEMBL2786030 | 0.91 | HSPA8 (0.38) | HSPA8DYRK1ACCNA2CDK2CCNA1 | |
| SCHEMBL2786035 | 0.91 | HSPA8 (0.38) | HSPA8DYRK1ACCNA2CDK2CCNA1 | |
| SCHEMBL13021272 | 0.88 | SRC (0.37) | CCNA2CDK2CCNA1EGFRSRC | |
| SCHEMBL12451475 | 0.86 | HSPA8 (0.39) | HSPA8DYRK1ACCNA2CDK2CCNA1 | |
| SCHEMBL2786054 | 0.84 | ADK (0.42) | EGFRSRCKDRP2RX3P2RX4 | |
| SCHEMBL13064459 | 0.84 | ADK (0.42) | EGFRSRCKDRP2RX3P2RX4 | |
| SCHEMBL13005503 | 0.80 | ATG7 (0.40) | DYRK1ACDK2CDK5EGFRSRC | |
| SCHEMBL3287276 | 0.80 | ATG7 (0.40) | DYRK1ACDK2CDK5EGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100297079-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTION | CHIMERIX, INC. (US) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297079-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTION | HAVCR2, EIF2AK2, OAT | HSPA8 2818/4885DYRK1A 4884/4885CCNA2 1835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.