Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13064474 | 0.94 | KMT2A (0.63) | HPGDKMT2ALMNAALDH1A1GAA | |
| SCHEMBL13064515 | 0.91 | HTT (0.58) | HPGDKMT2ALMNAALDH1A1TAS2R14 | |
| SCHEMBL2773524 | 0.88 | LMNA (0.51) | HPGDKMT2ALMNAALDH1A1TAS2R14 | |
| SCHEMBL13064393 | 0.85 | LMNA (0.60) | HPGDKMT2ALMNACNR1CNR2 | |
| SCHEMBL13065007 | 0.82 | LMNA (0.86) | HPGDKMT2ALMNAALDH1A1GAA | |
| SCHEMBL13064487 | 0.82 | LMNA (0.69) | HPGDKMT2ALMNAALDH1A1GAA | |
| SCHEMBL2776393 | 0.80 | TP53 (0.72) | KMT2AALDH1A1CNR1CNR2MAPT | |
| SCHEMBL314589 | 0.80 | TSHR (0.75) | KMT2AALDH1A1GAATSHRMAPT | |
| SCHEMBL13065194 | 0.80 | HPGD (0.73) | HPGDKMT2ALMNAALDH1A1CNR1 | |
| SCHEMBL302271 | 0.80 | LMNA (0.68) | HPGDKMT2ALMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010130638-A1 | SULFONAMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | EVOTEC AG (DE) | 2010-11-18 | — | — | WO | disclosed |