Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13064472 | 0.94 | HPGD (0.61) | KMT2AHPGDGAALMNAALDH1A1 | |
| SCHEMBL13064515 | 0.84 | HTT (0.58) | KMT2AHPGDLMNAALDH1A1HTT | |
| SCHEMBL13064390 | 0.83 | LMNA (0.62) | KMT2AHPGDGAALMNAHTT | |
| SCHEMBL2773524 | 0.81 | LMNA (0.51) | KMT2AHPGDLMNAALDH1A1HTT | |
| SCHEMBL13065006 | 0.81 | LMNA (0.91) | KMT2AHPGDGAALMNAALDH1A1 | |
| SCHEMBL303420 | 0.81 | LMNA (0.72) | KMT2AHPGDGAALMNAALDH1A1 | |
| SCHEMBL6973124 | 0.79 | GAA (0.73) | KMT2AGAAALDH1A1MEN1TSHR | |
| SCHEMBL30774072 | 0.79 | KCNH2 (0.78) | KMT2AHPGDGAALMNAALDH1A1 | |
| SCHEMBL1895548 | 0.79 | KCNH2 (0.78) | KMT2AHPGDGAALMNAALDH1A1 | |
| SCHEMBL13064477 | 0.78 | POLB (0.65) | KMT2ALMNAALDH1A1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010130638-A1 | SULFONAMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | EVOTEC AG (DE) | 2010-11-18 | — | — | WO | disclosed |