Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13064472 | 0.88 | HPGD (0.61) | LMNATAS2R14HTTALDH1A1TSHR | |
| SCHEMBL13064399 | 0.87 | CNR2 (0.48) | LMNATSHRCNR1CNR2KMT2A | |
| SCHEMBL13065210 | 0.87 | PKM (0.49) | LMNAALDH1A1MAPTCNR1CNR2 | |
| SCHEMBL13064515 | 0.85 | HTT (0.58) | LMNATAS2R14HTTALDH1A1TSHR | |
| SCHEMBL13064396 | 0.84 | LMNA (0.63) | LMNAHTTALDH1A1CNR1CNR2 | |
| SCHEMBL13065016 | 0.84 | CNR2 (0.56) | LMNAALDH1A1MAPTCNR1CNR2 | |
| SCHEMBL13064397 | 0.82 | PKM (0.47) | LMNAALDH1A1MAPTCNR1CNR2 | |
| SCHEMBL13065203 | 0.81 | PRKAA2 (0.55) | LMNAHTTALDH1A1TSHRCNR1 | |
| SCHEMBL13064488 | 0.81 | CNR2 (0.56) | LMNAHTTALDH1A1CNR1CNR2 | |
| SCHEMBL13064474 | 0.81 | KMT2A (0.63) | LMNAHTTALDH1A1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010130638-A1 | SULFONAMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | EVOTEC AG (DE) | 2010-11-18 | — | — | WO | disclosed |
| WO-2010130638-A1 | SULFONAMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | EVOTEC AG (DE) | 2010-11-18 | — | — | WO | disclosed |