Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 12/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13064486 | 0.94 | HTR2B (0.63) | HTR2BLMNAUSP2HPGDKMT2A | |
| SCHEMBL13065010 | 0.92 | HTR2B (0.51) | HTR2BLMNAUSP2HPGDKMT2A | |
| SCHEMBL13065222 | 0.89 | HTR2B (0.57) | HTR2BUSP2KMT2A | |
| SCHEMBL13065213 | 0.81 | LMNA (0.57) | LMNAHPGDKMT2A | |
| SCHEMBL1298775 | 0.80 | HTR2B (0.85) | HTR2BUSP2 | |
| SCHEMBL1298965 | 0.79 | HTR2B (0.77) | HTR2BUSP2KMT2A | |
| SCHEMBL13064487 | 0.79 | LMNA (0.69) | LMNAHPGDKMT2A | |
| SCHEMBL13064393 | 0.78 | LMNA (0.60) | LMNAHPGDKMT2A | |
| SCHEMBL13064472 | 0.78 | HPGD (0.61) | LMNAHPGDKMT2A | |
| SCHEMBL13065007 | 0.77 | LMNA (0.86) | LMNAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010130638-A1 | SULFONAMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | EVOTEC AG (DE) | 2010-11-18 | — | — | WO | disclosed |