Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 11/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13065005 | 0.92 | HTR2B (0.58) | HTR2BKMT2AUSP2LMNAHPGD | |
| SCHEMBL13065222 | 0.87 | HTR2B (0.57) | HTR2BKMT2AUSP2 | |
| SCHEMBL13064486 | 0.86 | HTR2B (0.63) | HTR2BKMT2AUSP2LMNAHPGD | |
| SCHEMBL13065011 | 0.85 | LMNA (0.55) | KMT2ALMNAHPGDMEN1 | |
| SCHEMBL13065009 | 0.82 | LMNA (0.50) | KMT2ALMNAHPGDMEN1 | |
| SCHEMBL13064516 | 0.81 | LMNA (0.60) | KMT2ALMNAHPGDMEN1 | |
| SCHEMBL13065202 | 0.80 | CNR2 (0.60) | KMT2ALMNAHPGDMEN1 | |
| SCHEMBL13065200 | 0.79 | LMNA (0.52) | KMT2ALMNAHPGDMEN1 | |
| SCHEMBL13064515 | 0.79 | HTT (0.58) | KMT2ALMNAHPGD | |
| SCHEMBL303313 | 0.78 | LMNA (0.57) | KMT2ALMNAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010130638-A1 | SULFONAMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | EVOTEC AG (DE) | 2010-11-18 | — | — | WO | disclosed |