Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28580716 | 0.77 | ALDH1A1 (0.36) | ALDH1A1CYP2A6MAPK1 | |
| SCHEMBL28505007 | 0.76 | RAB9A (0.41) | ALDH1A1HSD17B10HPGDRXFP1 | |
| SCHEMBL1681771 | 0.73 | PTGS2 (0.65) | BCAT2PTGS2PTPRC | |
| SCHEMBL3358969 | 0.73 | BCAT2 (0.48) | BCAT2PTGS2PDPK1BACE1ALDH1A1 | |
| SCHEMBL15751444 | 0.73 | CYP2A6 (0.41) | ALDH1A1CYP2A6HSD17B10CYP2B6CYP2E1 | |
| SCHEMBL920653 | 0.71 | BCAT2 (0.47) | BCAT2PTGS2PDPK1BACE1ALDH1A1 | |
| SCHEMBL18746178 | 0.71 | BCAT2 (0.47) | BCAT2PTGS2PDPK1BACE1ALDH1A1 | |
| SCHEMBL8649337 | 0.71 | CYP2A6 (0.60) | BCAT2PTGS2PDPK1BACE1ALDH1A1 | |
| SCHEMBL2782853 | 0.71 | PTGS2 (0.68) | BCAT2PTGS2 | |
| SCHEMBL2198638 | 0.71 | BCAT2 (0.52) | BCAT2PTGS2PDPK1BACE1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3129102-B1 | IODONIUM ANALOGS AS INHIBITORS OF NADPH OXIDASES AND OTHER FLAVIN DEHYDROGENASES; FORMULATIONS THEREOF; AND USES THEREOF | US HEALTH (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-111050730-B | Photoinitiator-modified polyacid polymers | 登特斯普伊德特雷有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-114835622-A | N-tert-butyl protection-3-substituted indole compound and preparation method thereof | 常州大学 | 2022-08-02 | — | — | CN | disclosed |
| US-10738047-B2 | Iodonium analogs as inhibitors of NADPH oxidases and other flavin dehydrogenases; formulations thereof; and uses thereof | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH (US) | 2020-08-11 | — | — | US | disclosed |
| US-20190048001-A1 | IODONIUM ANALOGS AS INHIBITORS OF NADPH OXIDASES AND OTHER FLAVIN DEHYDROGENASES; FORMULATIONS THEREOF; AND USES THEREOF | THE US SECRETARY DEPARTMENT OF HEALTH (US) | 2019-02-14 | — | — | US | disclosed |
| US-10131659-B2 | Iodonium analogs as inhibitors of NADPH oxidases and other flavin dehydrogenases; formulations thereof; and uses thereof | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2018-11-20 | — | — | US | disclosed |
| EP-3129102-A1 | IODONIUM ANALOGS AS INHIBITORS OF NADPH OXIDASES AND OTHER FLAVIN DEHYDROGENASES; FORMULATIONS THEREOF; AND USES THEREOF | The U.S.A. As Represented By The Secretary, Department Of Health And Human Services (US) | 2017-02-15 | — | — | EP | disclosed |
| US-20170029424-A1 | IODONIUM ANALOGS AS INHIBITORS OF NADPH OXIDASES AND OTHER FLAVIN DEHYDROGENASES; FORMULATIONS THEREOF; AND USES THEREOF | THE US SECRETARY DEPT OF HEALTH (US) | 2017-02-02 | — | — | US | disclosed |
| WO-2015157145-A1 | IODONIUM ANALOGS AS INHIBITORS OF NADPH OXIDASES AND OTHER FLAVIN DEHYDROGENASES; FORMULATIONS THEREOF; AND USES THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2015-10-15 | — | — | WO | disclosed |
| US-8053478-B1 | Antimicrobial diaryl iodonium compositions and method | Cornell Development Group, LLC (US) | 2011-11-08 | — | — | US | disclosed |
| US-7105707-B2 | Process for preparing alkynyl-substituted aromatic and heterocyclic compounds | PHARMACORE, INC. (US) | 2006-09-12 | — | — | US | disclosed |
| US-20050137402-A1 | Process for preparing alkynyl-substituted aromatic and heterocyclic compounds | DSM N.V. (NL) | 2005-06-23 | — | — | US | disclosed |
| US-6190834-B1 | FIRST RESIN BEING AN EPOXY RESIN, AND A SECOND EPOXY RESIN HAVING AN N-SUBSTITUTED CARBAMIC ACID ESTER GROUP AND A RADICAL POLYMERIC UNSATURATED BOND IN ITS SIDE CHAIN | HITACHI, LTD. (JP) | 2001-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190048001-A1 | IODONIUM ANALOGS AS INHIBITORS OF NADPH OXIDASES AND OTHER FLAVIN DEHYDROGENASES; FORMULATIONS THEREOF; AND USES THEREOF | NOX5, CYBB, NOX1 | BCAT2 2721/4885PTGS2 340/4885PDPK1 2569/4885 |
| US-10131659-B2 | Iodonium analogs as inhibitors of NADPH oxidases and other flavin dehydrogenases; formulations thereof; and uses thereof | NOX5, CYBB, NOX1 | BCAT2 2721/4885PTGS2 340/4885PDPK1 2569/4885 |
| US-20170029424-A1 | IODONIUM ANALOGS AS INHIBITORS OF NADPH OXIDASES AND OTHER FLAVIN DEHYDROGENASES; FORMULATIONS THEREOF; AND USES THEREOF | NOX5, CYBB, NOX1 | BCAT2 2721/4885PTGS2 340/4885PDPK1 2569/4885 |
| US-20050137402-A1 | Process for preparing alkynyl-substituted aromatic and heterocyclic compounds | NAT1, B3GNT2, NISCH | BCAT2 1868/4885PTGS2 2836/4885PDPK1 889/4885 |
| US-10738047-B2 | Iodonium analogs as inhibitors of NADPH oxidases and other flavin dehydrogenases; formulations thereof; and uses thereof | NOX5, CYBB, NOX1 | BCAT2 2721/4885PTGS2 340/4885PDPK1 2569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.