Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306709 | 0.89 | ALDH1A1 (0.49) | L3MBTL1LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL1307208 | 0.85 | TRPM4 (0.41) | L3MBTL1LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL1305163 | 0.84 | TDP1 (0.49) | L3MBTL1LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL1307100 | 0.83 | PTPN1 (0.45) | LMNAALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL1306803 | 0.83 | HPGD (0.43) | L3MBTL1LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL1306577 | 0.81 | DRD3 (0.46) | KDM4ETDP1 | |
| SCHEMBL1326044 | 0.80 | TRPM4 (0.41) | L3MBTL1LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL1306490 | 0.80 | KDM4E (0.47) | L3MBTL1LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL1306510 | 0.79 | TRPM4 (0.41) | L3MBTL1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL1306160 | 0.78 | KMT2A (0.45) | ALDH1A1KDM4EHPGDTDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053435-B2 | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-11-08 | — | — | US | disclosed |