Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | OGG1 | O15527 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306839 | 1.00 | CNR2 (0.40) | CNR2CNR1ALDH1A1KDM4EHPGD | |
| SCHEMBL1308080 | 0.97 | SIGMAR1 (0.39) | CNR2CNR1ALDH1A1KDM4EHPGD | |
| SCHEMBL1308081 | 0.97 | SIGMAR1 (0.39) | CNR2CNR1ALDH1A1KDM4EHPGD | |
| SCHEMBL1306209 | 0.92 | ALDH1A1 (0.44) | CNR2ALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL1306207 | 0.92 | ALDH1A1 (0.44) | CNR2ALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL1307233 | 0.90 | KDM4E (0.40) | CNR2CNR1ALDH1A1KDM4EHPGD | |
| SCHEMBL1306054 | 0.90 | P2RX3 (0.39) | ALDH1A1KDM4EHPGDTDP1NPSR1 | |
| SCHEMBL1306050 | 0.90 | P2RX3 (0.39) | ALDH1A1KDM4EHPGDTDP1NPSR1 | |
| SCHEMBL1307230 | 0.90 | KDM4E (0.40) | CNR2CNR1ALDH1A1KDM4EHPGD | |
| SCHEMBL29488479 | 0.90 | P2RX3 (0.39) | ALDH1A1KDM4EHPGDTDP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053435-B2 | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-11-08 | — | — | US | disclosed |