SCHEMBL19495100

SCHEMBL19495100

CCN(CC)c1ccc2c(c1)Oc1cc(N(CC)CC)c(OC)cc1C2(OC)c1ccccc1C=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
POLB P06746 1/20 0.38
GFER P55789 1/20 0.38
CA12 O43570 5/20 0.38
CA9 Q16790 5/20 0.38
CA1 P00915 4/20 0.38
CA2 P00918 4/20 0.38
CA3 P07451 4/20 0.38
CA4 P22748 4/20 0.38
CA6 P23280 4/20 0.38
CA5A P35218 4/20 0.38
CA7 P43166 4/20 0.38
CA13 Q8N1Q1 4/20 0.38
CA14 Q9ULX7 4/20 0.38
CA5B Q9Y2D0 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13135701 0.92 ALDH1A1 (0.51) ALDH1A1L3MBTL1MEN1KMT2ARAB9A
SCHEMBL19494876 0.88 ALDH1A1 (0.51) ALDH1A1L3MBTL1MEN1KMT2ARAB9A
SCHEMBL19494797 0.84 ALDH1A1 (0.48) ALDH1A1L3MBTL1MEN1KMT2ARAB9A
SCHEMBL19495007 0.82 ALDH1A1 (0.41) ALDH1A1L3MBTL1MEN1KMT2ACA12
SCHEMBL19494853 0.79 CYP3A4 (0.53) ALDH1A1L3MBTL1MEN1KMT2ARAB9A
SCHEMBL13069672 0.77 ALDH1A1 (0.46) ALDH1A1L3MBTL1MEN1KMT2ARAB9A
SCHEMBL20369125 0.75 ALDH1A1 (0.44) ALDH1A1L3MBTL1MEN1KMT2ARAB9A
SCHEMBL19014826 0.73 FTO (0.46) ALDH1A1MEN1KMT2ARAB9ANPC1
SCHEMBL25776271 0.72 LMNA (0.38) ALDH1A1MEN1KMT2AMAPTHPGD
SCHEMBL2950989 0.70 ALDH1A1 (1.00) ALDH1A1L3MBTL1MEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3235876-A1 QUENCHER Wako Pure Chemical Industries, Ltd. (JP) 2017-10-25 EP disclosed