SCHEMBL13069751

SCHEMBL13069751

Cc1ccc(F)c(C)c1[C@@H](C)O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29628557 0.83 CHRM2 (0.34) MEN1KMT2AACHE
SCHEMBL20872550 0.83 CHRM2 (0.34) MEN1KMT2AACHE
SCHEMBL22222494 0.82 ACHE (0.33) ACHE
SCHEMBL23393525 0.79 MET (0.33) MEN1KMT2A
SCHEMBL3093413 0.78 MEN1 (0.33) MEN1KMT2AACHE
SCHEMBL3097748 0.75 CHRM2 (0.32) MEN1KMT2A
SCHEMBL24373240 0.75 MEN1 (0.32) MEN1KMT2A
SCHEMBL29478802 0.75 MEN1 (0.32) MEN1KMT2A
SCHEMBL22728357 0.74 ACHE (0.46) MEN1KMT2AACHE
SCHEMBL13069749 0.72 CHRM2 (0.36) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1959955-B1 METHOD OF TREATING ABNORMAL CELL GROWTH PFIZER PROD INC (US) 2010-11-17 EP disclosed