Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | RRM1 | P23921 | 2/20 | 0.36 |
| ▸ | RRM2B | Q7LG56 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13069750 | 0.84 | CHRM2 (0.40) | CHRM2CHRM1RRM1RRM2BTSHR | |
| SCHEMBL28022516 | 0.75 | CES2 (0.43) | TSHRPGRPTGS1PDE4AMMP12 | |
| SCHEMBL13069751 | 0.72 | DAO (0.33) | ACHE | |
| SCHEMBL5005733 | 0.72 | MET (0.46) | — | |
| SCHEMBL1582077 | 0.72 | MET (0.46) | — | |
| SCHEMBL5008088 | 0.72 | MET (0.46) | — | |
| SCHEMBL22222494 | 0.72 | ACHE (0.33) | PTGS1ACHE | |
| SCHEMBL11570628 | 0.70 | CD44 (0.38) | TSHRTDP1MMP12 | |
| SCHEMBL22201767 | 0.69 | HDAC3 (0.41) | TSHRPGRPTGS1PDE4AHDAC1 | |
| SCHEMBL28758397 | 0.69 | TSHR (0.39) | TSHRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1959955-B1 | METHOD OF TREATING ABNORMAL CELL GROWTH | PFIZER PROD INC (US) | 2010-11-17 | — | — | EP | disclosed |