SCHEMBL13070367

SCHEMBL13070367

C1=Cc2c(c3ccccc3n2-c2cc(-c3ccccn3)nc(-c3cccc(-n4c5ccccc5c5cnccc54)n3)c2)CN1

nearest known ligand 0.32

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
ALPL P05186 1/20 0.30
HSP90AA1 P07900 1/20 0.30
ALPI P09923 1/20 0.30
ALPG P10696 1/20 0.30
ALOX15 P16050 1/20 0.30
MAPK1 P28482 1/20 0.30
CCR1 P32246 1/20 0.30
HTT P42858 1/20 0.30
CCR5 P51681 1/20 0.30
CCR8 P51685 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13070194 0.87 MAOA (0.32)
SCHEMBL13892742 0.85 MAOA (0.33)
SCHEMBL13006528 0.84 CCR1 (0.41) KDM4ELMNATP53ALPLHSP90AA1
SCHEMBL13569478 0.84
SCHEMBL13070191 0.84 MAPT (0.36)
SCHEMBL13892741 0.84 KARS1 (0.30)
SCHEMBL13569550 0.82 HTR1A (0.32)
SCHEMBL16689884 0.82 CCR1 (0.34) KDM4ELMNATP53ALPLHSP90AA1
SCHEMBL9922154 0.81 MAOA (0.32)
SCHEMBL16689894 0.81 CCR1 (0.33) KDM4ELMNATP53ALPLHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2246351-A1 COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE BONDED WITH SUBSTITUTED PYRIDYL GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE Hodogaya Chemical Co., Ltd. (JP) 2010-11-03 EP disclosed