Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907388 | 0.86 | CNR2 (0.44) | TSHRCYP1A2CYP3A4ABCB11HTR2A | |
| SCHEMBL6135476 | 0.83 | NPSR1 (0.50) | TSHRCYP1A2CYP3A4ABCB11HTR2A | |
| SCHEMBL2490473 | 0.83 | CYP3A4 (0.58) | TSHRCYP1A2CYP3A4ABCB11HTR2A | |
| SCHEMBL6135621 | 0.83 | NPSR1 (0.50) | TSHRCYP1A2CYP3A4ABCB11HTR2A | |
| SCHEMBL204187 | 0.83 | NPSR1 (0.50) | TSHRCYP1A2CYP3A4ABCB11HTR2A | |
| SCHEMBL27731921 | 0.83 | PIN1 (0.51) | TSHRPIN1MMP8SMN1; SMN2MAPT | |
| SCHEMBL1455978 | 0.83 | PIN1 (0.51) | TSHRPIN1MMP8SMN1; SMN2MAPT | |
| SCHEMBL27752471 | 0.83 | PIN1 (0.51) | TSHRPIN1MMP8SMN1; SMN2MAPT | |
| SCHEMBL1509089 | 0.82 | L3MBTL1 (0.51) | TSHRCYP1A2CYP3A4ABCB11HTR2A | |
| SCHEMBL1972148 | 0.82 | L3MBTL1 (0.51) | TSHRCYP1A2CYP3A4ABCB11HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |