Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8347783 | 0.86 | MEN1 (0.65) | QPCTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12963493 | 0.84 | MEN1 (0.51) | LMNAMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL12933367 | 0.83 | LMNA (0.47) | LMNAMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL8345899 | 0.79 | MCHR1 (0.56) | LMNAMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL12963481 | 0.77 | MCHR1 (0.54) | LMNAMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL12933366 | 0.76 | MCHR1 (0.48) | LMNAMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL12963479 | 0.73 | SMN1; SMN2 (0.49) | MEN1KMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL12933363 | 0.72 | IMPDH2 (0.54) | MEN1KMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL12963485 | 0.72 | MAPT (0.52) | MEN1KMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL1064792 | 0.72 | HDAC1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7838520-B2 | Inhibitors of histone deacetylase | METHYLGENE, INC. (CA) | 2010-11-23 | — | — | US | disclosed |