Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13076286 | 0.77 | DRD2 (0.34) | MGLLLMNA | |
| SCHEMBL13076225 | 0.77 | DRD2 (0.34) | MGLLLMNA | |
| SCHEMBL9571886 | 0.75 | ESR1 (0.46) | ALDH1A1HSD17B10LMNA | |
| SCHEMBL13075828 | 0.74 | CYP1A2 (0.41) | ALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL28214402 | 0.74 | CES1 (0.45) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL21663226 | 0.71 | PIK3CA (0.42) | MEN1KMT2A | |
| SCHEMBL9132367 | 0.70 | KMT2A (0.52) | THRATHRBKMT2AHPGDHSD17B10 | |
| SCHEMBL1499301 | 0.70 | ALOX5 (0.44) | THRATHRBMEN1KMT2AMGLL | |
| SCHEMBL9133875 | 0.70 | CYP4A11 (0.57) | MGLLALDH1A1HPGDHSD17B10 | |
| SCHEMBL8804536 | 0.69 | TAAR1 (0.45) | THRATHRBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010124385-A1 | PROCESSES FOR THE PREPARATION OF RIVAROXABAN AND INTERMEDIATES THEREOF | APOTEX PHARMACHEM INC. (CA) | 2010-11-04 | — | — | WO | disclosed |