Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13076225 | 1.00 | DRD2 (0.34) | DRD2DRD3GAAMAPTMGLL | |
| SCHEMBL13075832 | 0.77 | THRA (0.39) | MGLLLMNA | |
| SCHEMBL9571886 | 0.68 | ESR1 (0.46) | LMNA | |
| SCHEMBL13075828 | 0.67 | CYP1A2 (0.41) | DRD3GAAMAPTLMNA | |
| SCHEMBL28214402 | 0.67 | CES1 (0.45) | MAPTLMNA | |
| SCHEMBL11589263 | 0.65 | CYP1A2 (0.48) | MAPTLMNAHTT | |
| SCHEMBL11795190 | 0.65 | PKM (0.48) | GAAMAPTLMNAHTT | |
| SCHEMBL116673 | 0.65 | F10 (0.44) | — | |
| SCHEMBL7722222 | 0.65 | F10 (0.44) | — | |
| SCHEMBL116674 | 0.65 | F10 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010124385-A1 | PROCESSES FOR THE PREPARATION OF RIVAROXABAN AND INTERMEDIATES THEREOF | APOTEX PHARMACHEM INC. (CA) | 2010-11-04 | — | — | WO | disclosed |