SCHEMBL1499301

SCHEMBL1499301

O=C(c1ccc(CCC2CO2)cc1)c1ccc(CCC2CO2)cc1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.44
THRA P10827 1/20 0.44
THRB P10828 1/20 0.44
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
SLC6A3 Q01959 1/20 0.40
MGLL Q99685 3/20 0.39
SRD5A2 P31213 2/20 0.39
S1PR1 P21453 1/20 0.38
CA3 P07451 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1499512 0.93 ALDH1A1 (0.47) MEN1KMT2AMGLLSRD5A2
SCHEMBL9132367 0.85 KMT2A (0.52) ALOX5THRATHRBKMT2A
SCHEMBL9133875 0.81 CYP4A11 (0.57) MGLL
SCHEMBL9132885 0.80 ESR1 (0.49) THRBMEN1KMT2ASLC6A2SLC6A3
SCHEMBL27692231 0.78 THRA (0.46) THRATHRBMEN1KMT2AMGLL
SCHEMBL4678555 0.77 ALOX5 (0.41) ALOX5THRATHRBMEN1KMT2A
SCHEMBL9132340 0.76 PARP10 (0.45) MEN1KMT2AMGLL
SCHEMBL8803172 0.76 DRD4 (0.50) ALOX5MEN1KMT2ASLC6A2SLC6A4
SCHEMBL8804583 0.76 DRD4 (0.51) ALOX5MEN1KMT2ASLC6A2SLC6A4
SCHEMBL411370 0.76 TAAR1 (0.45) ALOX5MEN1KMT2ASLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3710159-A1 CATALYST COMPONENTS FOR PROPYLENE POLYMERIZATION W. R. Grace & Co. - Conn. (US) 2020-09-23 EP claimed
US-8344079-B2 Molar ratio modifications to larger polyolefin catalysts BASF CORPORATION (US) 2013-01-01 US claimed
JP-2011508053-A 2011-03-10 JP claimed
EP-2242776-A1 MOLAR RATIO MODIFICATIONS TO LARGER POLYOLEFIN CATALYSTS BASF Corporation (US) 2010-10-27 EP claimed
WO-2009088596-A1 MOLAR RATIO MODIFICATIONS TO LARGER POLYOLEFIN CATALYSTS BASF CATALYSTS LLC (US) 2009-07-16 WO claimed
US-20090171044-A1 MOLAR RATIO MODIFICATIONS TO LARGER POLYOLEFIN CATALYSTS BASF CATALYSTS LLC (US) 2009-07-02 US claimed
US-20260103548-A1 PROCESS FOR PRODUCING POLYPROPYLENE-ETHYLENE RANDOM COPOLYMER RESIN WITH SUSTAINABLE REACTOR OPERABILITY W. R. GRACE & CO.-CONN. 2026-04-16 US disclosed
US-20250235842-A1 GAS-PHASE PROCESS FOR MAKING POLYPROPYLENE RANDOM COPOLYMERS W.R. GRACE & CO.-CONN (US) 2025-07-24 US disclosed
US-20250145745-A1 HIGH MFR POLYPROPYLENE FOR MELTBLOWN NONWOVEN APPLICATIONS W. R. GRACE & CO.-CONN. 2025-05-08 US disclosed
US-12240925-B2 Process for preparing solid catalyst components for olefin polymerization W. R. GRACE & CO.- CONN. (US) 2025-03-04 US disclosed
US-20240392047-A1 CATALYST COMPONENT FOR PROPYLENE POLYMERIZATION WITH IMPROVED CATALYST PERFORMANCE W.R. GRACE & CO.-CONN (US) 2024-11-28 US disclosed
CN-119013320-A High MFR polypropylene for melt blown nonwoven applications 格雷斯公司 2024-11-22 CN disclosed
US-20240343840-A1 PROCESS FOR PRODUCING POLYOLEFIN GRANULAR RESIN WITH INCREASED SETTLED BULK DENSITY W.R. GRACE & CO.-CONN. (US) 2024-10-17 US disclosed
US-20040260039-A1 Process for producing organic compound epoxy resin composition, cured article obtained from the epoxy resin, and semiconductor device obtained with epoxy resin MITSUI CHEMICALS, INC. (JP) 2004-12-23 US disclosed
EP-0972776-B1 A phosphine sulfide, a manufacturing process therefor and a use thereof MITSUI CHEMICALS INC (JP) 2003-04-23 EP disclosed
EP-0950649-B1 A process for preparing oxyalkylene derivatives in the presence of phosphine oxides MITSUI CHEMICALS INC (JP) 2003-03-26 EP disclosed
US-6153794-A Phosphine sulfide, a manufacturing process therefor and use thereof MITSUI CHEMICALS, INC. (JP) 2000-11-28 US disclosed
US-6130346-A ESTERIFICATION, CARBONATION, SULFONATION, ETHERIFICATION MITSUI CHEMICALS, INC. (JP) 2000-10-10 US disclosed
EP-0972776-A1 A phosphine sulfide, a manufacturing process therefor and a use thereof Mitsui Chemicals, Inc. (JP) 2000-01-19 EP disclosed
EP-0950649-A1 A process for preparing oxyalkylene derivatives in the presence of phosphine oxides Mitsui Chemicals, Inc. (JP) 1999-10-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12240925-B2 Process for preparing solid catalyst components for olefin polymerization POF1B, PPOX, OGFOD1 ALOX5 727/4885THRA 2684/4885THRB 3700/4885
US-20260103548-A1 PROCESS FOR PRODUCING POLYPROPYLENE-ETHYLENE RANDOM COPOLYMER RESIN WITH SUSTAINABLE REACTOR OPERABILITY CCT4, PTGER1, TCP1 ALOX5 355/4885THRA 1345/4885THRB 2073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.