Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 16/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.50 |
| ▸ | TLR2 | O60603 | 1/20 | 0.50 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.50 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13043498 | 0.88 | ERN1 (0.50) | ERN1TLR2TLR1TLR6 | |
| SCHEMBL3477937 | 0.84 | ERN1 (0.45) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL3744167 | 0.83 | ERN1 (0.43) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL28803580 | 0.83 | ALDH1A1 (0.53) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL5144556 | 0.79 | ERN1 (0.56) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL1527154 | 0.76 | ERN1 (0.69) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL12766863 | 0.75 | ERN1 (1.00) | ERN1 | |
| SCHEMBL28803582 | 0.74 | ALDH1A1 (0.59) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL13752271 | 0.73 | MGAM (0.53) | ERN1ALDH1A1LMNA | |
| SCHEMBL13605931 | 0.73 | ERN1 (0.59) | ERN1ALDH1A1TRIM24TYRTRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450365-B2 | Efficient synthesis of galanthamine | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-05-28 | — | — | US | disclosed |
| US-8362283-B2 | Cross-conjugated 2,5-cyclohexadienone and related synthesis methods | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-01-29 | — | — | US | disclosed |
| US-20100292466-A1 | Efficient Synthesis Of Galanthamine | BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292466-A1 | Efficient Synthesis Of Galanthamine | GALR2, GALR1, OPRK1 | ERN1 1917/4885ALDH1A1 1200/4885TRIM24 466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.