Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 17/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.41 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13078747 | 0.84 | ERN1 (0.60) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL3744167 | 0.81 | ERN1 (0.43) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL13043498 | 0.78 | ERN1 (0.50) | ERN1TLR2TLR1TLR6 | |
| SCHEMBL1268203 | 0.76 | ALDH1A1 (0.65) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL13079722 | 0.74 | ERN1 (0.33) | ERN1ALDH1A1 | |
| SCHEMBL3744230 | 0.74 | ERN1 (0.33) | ERN1ALDH1A1 | |
| SCHEMBL22974979 | 0.69 | ALDH1A1 (0.50) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL28803580 | 0.68 | ALDH1A1 (0.53) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL1527154 | 0.68 | ERN1 (0.69) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL3697133 | 0.66 | ALDH1A3 (0.57) | ALDH1A1TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293927-B2 | Efficient synthesis of morphine and codeine | BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-10-23 | — | — | US | disclosed |
| US-8293927-B2 | Efficient synthesis of morphine and codeine | BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-10-23 | — | — | US | disclosed |
| WO-2010132570-A1 | SYNTHESIS OF MORPHINE AND RELATED DERIVATIVES | BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-11-18 | — | — | WO | disclosed |
| US-20100292475-A1 | Efficient Synthesis Of Morphine And Codeine | BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM | 2010-11-18 | — | — | US | disclosed |
| US-20100292489-A1 | Cross-conjugated 2,5-cyclohexadienone and related synthesis methods | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2010-11-18 | — | — | US | disclosed |
| US-20100292475-A1 | Efficient Synthesis Of Morphine And Codeine | BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292489-A1 | Cross-conjugated 2,5-cyclohexadienone and related synthesis methods | OPRK1, GALR2, OPRM1 | ERN1 3315/4885TLR2 1230/4885TLR1 3922/4885 |
| US-20100292475-A1 | Efficient Synthesis Of Morphine And Codeine | OPRK1, OPRM1, OPRL1 | ERN1 1030/4885TLR2 2821/4885TLR1 3061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.