Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC43A1 | O75387 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12966926 | 1.00 | GAA (0.42) | GAAABCB1TSHRPTGES2TDP1 | |
| SCHEMBL13965711 | 1.00 | GAA (0.42) | GAAABCB1TSHRPTGES2TDP1 | |
| SCHEMBL15241392 | 0.83 | LGALS9 (0.44) | GAAABCB1TSHRTDP1LMNA | |
| SCHEMBL264538 | 0.83 | GAA (0.39) | GAAABCB1TSHRTDP1LMNA | |
| SCHEMBL16647467 | 0.83 | LGALS9 (0.44) | GAAABCB1TSHRTDP1LMNA | |
| SCHEMBL14929034 | 0.83 | GAA (0.39) | GAAABCB1TSHRTDP1LMNA | |
| SCHEMBL18561533 | 0.83 | GAA (0.39) | GAAABCB1TSHRTDP1LMNA | |
| SCHEMBL15908419 | 0.83 | GAA (0.39) | GAAABCB1TSHRTDP1LMNA | |
| SCHEMBL21418908 | 0.81 | ALDH1A1 (0.49) | GAATDP1LMNAKMT2AMEN1 | |
| SCHEMBL21418911 | 0.81 | ALDH1A1 (0.49) | GAATDP1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100291031-A2 | BICYCLIC NUCLEOSIDES AND NUCLEOTIDES AS THERAPEUTIC AGENTS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100291031-A2 | BICYCLIC NUCLEOSIDES AND NUCLEOTIDES AS THERAPEUTIC AGENTS | SLC29A2, NT5C2, NUDT1 | GAA 799/4885ABCB1 144/4885TSHR 4431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.