SCHEMBL13080604

SCHEMBL13080604

Cc1ccc2c(c1)C(=O)C(c1ccc(O)c(C)c1)(c1ccc(O)c(C)c1)c1cc(C)ccc1-2

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.52
ESR2 Q92731 3/20 0.52
MEN1 O00255 2/20 0.46
LMNA P02545 2/20 0.46
MAPT P10636 2/20 0.46
KMT2A Q03164 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
XBP1 P17861 1/20 0.46
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA4 P22748 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
TDP1 Q9NUW8 3/20 0.43
TP53 P04637 1/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
POLB P06746 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
PKM P14618 1/20 0.40
CNR1 P21554 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL899482 0.87 ESR1 (0.68) ESR1ESR2MEN1LMNAMAPT
SCHEMBL13080602 0.86 ESR1 (0.52) ESR1ESR2MEN1LMNAMAPT
SCHEMBL170128 0.84 CNR1 (0.52) ESR1ESR2CA1CA2CA4
SCHEMBL172169 0.80 ESR1 (0.77) ESR1ESR2MEN1LMNAMAPT
SCHEMBL13080606 0.78 ESR1 (0.73) ESR1ESR2MEN1LMNAMAPT
SCHEMBL2675832 0.77 ESR1 (0.68) ESR1ESR2MEN1LMNAMAPT
SCHEMBL18648071 0.76 TRPA1 (0.52) ESR1ESR2MEN1LMNAMAPT
SCHEMBL12924695 0.74 ESR1 (0.50) ESR1ESR2MEN1LMNAMAPT
SCHEMBL900305 0.72 ESR1 (0.45) ESR1ESR2MEN1LMNAMAPT
SCHEMBL4072602 0.72 ESR1 (0.64) ESR1ESR2MEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8283433-B2 Polycarbonate resin and electrophotographic photosensitive body using the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-10-09 US disclosed
US-8283433-B2 Polycarbonate resin and electrophotographic photosensitive body using the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-10-09 US disclosed
US-20100047703-A1 POLYCARBONATE RESIN AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY USING THE SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-02-25 US disclosed
US-20100047703-A1 POLYCARBONATE RESIN AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY USING THE SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-02-25 US disclosed
EP-2048180-A1 POLYCARBONATE RESIN AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY USING THE SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2009-04-15 EP disclosed