SCHEMBL170128

SCHEMBL170128

Cc1ccc2c(c1)C(=O)C(c1ccc(O)cc1)(c1ccc(O)cc1)c1cc(C)ccc1-2

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 3/20 0.52
GPR55 Q9Y2T6 3/20 0.52
PKM P14618 1/20 0.52
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA7 P43166 2/20 0.47
CA9 Q16790 2/20 0.47
CA4 P22748 1/20 0.47
HTT P42858 1/20 0.38
GPR35 Q9HC97 1/20 0.38
LCK P06239 1/20 0.37
PDE4D Q08499 5/20 0.36
MAOB P27338 2/20 0.36
MAOA P21397 1/20 0.36
CHRM2 P08172 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
KCNH2 Q12809 1/20 0.36
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
ACHE P22303 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL900053 0.85 CNR1 (0.54) CNR1GPR55PKMCA1CA2
SCHEMBL172084 0.85 CNR1 (0.49) CNR1GPR55PKMCA1CA2
SCHEMBL13080604 0.84 ESR1 (0.52) CNR1GPR55PKMCA1CA2
SCHEMBL9172820 0.83 CNR1 (0.49) CNR1GPR55PKMCA1CA2
SCHEMBL15587210 0.80 GPR55 (0.49) CNR1GPR55PKMHTTGPR35
SCHEMBL12963010 0.79 PKM (0.48) CNR1GPR55PKMPDE4DMAOB
SCHEMBL9175901 0.78 ESR1 (0.55) CNR1GPR55PKMHTTGPR35
SCHEMBL15613359 0.76 ESR2 (0.53) CNR1GPR55PKMHTTGPR35
SCHEMBL2673844 0.75 CNR1 (0.50) CNR1GPR55PKMCA1CA2
SCHEMBL12510697 0.75 ACHE (0.44) CNR1GPR55PKMPDE4DMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8283433-B2 Polycarbonate resin and electrophotographic photosensitive body using the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-10-09 US disclosed
US-8283433-B2 Polycarbonate resin and electrophotographic photosensitive body using the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-10-09 US disclosed
EP-2048180-B1 POLYCARBONATE RESIN AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY USING THE SAME MITSUBISHI GAS CHEMICAL CO (JP) 2012-03-07 EP disclosed
US-20100047703-A1 POLYCARBONATE RESIN AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY USING THE SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-02-25 US disclosed
US-20100047703-A1 POLYCARBONATE RESIN AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY USING THE SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-02-25 US disclosed
EP-2048180-A1 POLYCARBONATE RESIN AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY USING THE SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2009-04-15 EP disclosed