Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | HTR2A | P28223 | 2/20 | 0.70 |
| ▸ | HTR2B | P41595 | 2/20 | 0.70 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.70 |
| ▸ | HTR1B | P28222 | 6/20 | 0.46 |
| ▸ | HTR1D | P28221 | 5/20 | 0.46 |
| ▸ | HTR5A | P47898 | 4/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR1E | P28566 | 1/20 | 0.44 |
| ▸ | HTR1F | P30939 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13081207 | 0.87 | LMNA (0.66) | HTR1ALMNAHTR2AHTR2BADRA2B | |
| SCHEMBL13081208 | 0.85 | LMNA (0.64) | HTR1ALMNAHTR2AHTR2BADRA2B | |
| Almotriptan SCHEMBL29396422 | 0.83 | HTR1A (1.00) | HTR1ALMNAHTR2AHTR2BADRA2B | |
| Almotriptan SCHEMBL1957 | 0.83 | HTR1A (1.00) | HTR1ALMNAHTR2AHTR2BADRA2B | |
| Almotriptan SCHEMBL3273179 | 0.83 | HTR1A (1.00) | HTR1ALMNAHTR2AHTR2BADRA2B | |
| Almotriptan SCHEMBL1774275 | 0.82 | HTR1A (0.90) | HTR1ALMNAHTR2AHTR2BADRA2B | |
| SCHEMBL1437 | 0.82 | HTR1A (0.98) | HTR1ALMNAHTR2AHTR2BADRA2B | |
| Almotriptan SCHEMBL2166 | 0.82 | HTR1A (0.98) | HTR1ALMNAHTR2AHTR2BADRA2B | |
| SCHEMBL2791148 | 0.81 | HTR1A (0.74) | HTR1ALMNAHTR2AHTR2BADRA2B | |
| Almotriptan SCHEMBL2761861 | 0.81 | HTR1A (0.86) | HTR1ALMNAHTR2AHTR2BADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100292290-A1 | NOVEL PROCESS TO PREPARE ALMOTRIPTAN | MYLAN DEVELOPMENT CENTRE PRIVATE LIMITED (IN) | 2010-11-18 | — | — | US | disclosed |
| WO-2009016414-A1 | NOVEL PROCESS | GENERICS [UK] LIMITED (GB) | 2009-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292290-A1 | NOVEL PROCESS TO PREPARE ALMOTRIPTAN | HTR5A, LPXN, AGPAT5 | HTR1A 36/4885LMNA 1462/4885HTR2A 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.