SCHEMBL13083237

SCHEMBL13083237

CC(=O)OC(c1ccccc1)c1ccccc1N=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
CYP3A4 P08684 1/20 0.45
PABPC1 P11940 1/20 0.40
APOBEC3A P31941 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40
TSHR P16473 1/20 0.40
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
HSD17B10 Q99714 1/20 0.36
KMT2A Q03164 2/20 0.36
GLS O94925 2/20 0.35
IDO1 P14902 1/20 0.35
TDO2 P48775 1/20 0.35
HPGD P15428 2/20 0.34
HCAR2 Q8TDS4 1/20 0.34
CYP19A1 P11511 2/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
MEN1 O00255 1/20 0.34
SRD5A2 P31213 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25466151 0.86 ALDH1A1 (0.53) ALDH1A1CYP3A4PABPC1APOBEC3AAPOBEC3G
SCHEMBL1202828 0.80 ALDH1A1 (0.58) ALDH1A1CYP3A4PABPC1APOBEC3AAPOBEC3G
Hydrazine SCHEMBL18138498 0.77 ALDH1A1 (0.55) ALDH1A1CYP3A4PABPC1APOBEC3AAPOBEC3G
SCHEMBL276079 0.77 PTGS2 (0.49) ALDH1A1CYP3A4ESR1ESR2
SCHEMBL16002841 0.76 ALDH1A1 (0.49) ALDH1A1CYP3A4PABPC1APOBEC3AAPOBEC3G
SCHEMBL6895354 0.74 ALDH1A1 (0.52) ALDH1A1CYP3A4TSHRHSD17B10KMT2A
SCHEMBL10627201 0.74 FAAH (0.55)
SCHEMBL486678 0.73 ALDH1A1 (0.63) ALDH1A1CYP3A4PABPC1APOBEC3AAPOBEC3G
SCHEMBL11130696 0.71 ALDH1A1 (0.49) ALDH1A1CYP3A4PABPC1APOBEC3AAPOBEC3G
SCHEMBL14798131 0.71 ALDH1A1 (0.61) ALDH1A1CYP3A4PABPC1APOBEC3AAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8283100-B2 Color forming compositions and associated methods HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2012-10-09 US disclosed