Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 5/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 5/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL686481 | 0.97 | CRHR1 (0.36) | PDE4BCRHR1MAPK13MAPK12MAPK11 | |
| SCHEMBL13085060 | 0.95 | CRHR1 (0.36) | PDE4BCRHR1OPRL1MAPK13MAPK12 | |
| SCHEMBL13085125 | 0.94 | CRHR1 (0.35) | PDE4BCRHR1OPRL1CCNT1CDK4 | |
| SCHEMBL13084989 | 0.94 | CRHR1 (0.35) | PDE4BCRHR1MAPK13MAPK12MAPK11 | |
| SCHEMBL10089918 | 0.93 | NTRK1 (0.34) | CRHR1GRM4MALT1 | |
| SCHEMBL13084846 | 0.93 | RORC (0.34) | PDE4BCRHR1OPRL1MAPK13MAPK12 | |
| SCHEMBL13085405 | 0.92 | CRHR1 (0.37) | PDE4BCRHR1MAPK13MAPK12MAPK11 | |
| SCHEMBL685487 | 0.92 | CRHR1 (0.38) | PDE4BCRHR1MAPK13MAPK12MAPK11 | |
| SCHEMBL13085202 | 0.92 | CRHR1 (0.36) | PDE4BCRHR1MAPK13MAPK12MAPK11 | |
| SCHEMBL13085145 | 0.91 | CRHR1 (0.37) | CRHR1CNR2CNR1CRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324390-B2 | Tetrazole-substituted anthranilamides as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-12-04 | — | — | US | disclosed |
| US-8324390-B2 | Tetrazole-substituted anthranilamides as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-12-04 | — | — | US | disclosed |
| US-20100256195-A1 | Tetrazole-substituted anthranilamides as pesticides | BAYER CROPSCIENCE AG (DE) | 2010-10-07 | — | — | US | disclosed |
| US-20100256195-A1 | Tetrazole-substituted anthranilamides as pesticides | BAYER CROPSCIENCE AG (DE) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256195-A1 | Tetrazole-substituted anthranilamides as pesticides | ANTXR2, PNISR, H1-5 | PDE4B 3200/4885CRHR1 4225/4885OPRL1 3317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.